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流产后常见精神障碍的长期发生率和复发率。一项荷兰前瞻性队列研究。

Long-term incidence and recurrence of common mental disorders after abortion. A Dutch prospective cohort study.

机构信息

Department of Interdisciplinary Social Science, Utrecht University, Utrecht, The Netherlands.

Netherlands Institute of Mental Health and Addiction (Trimbos Institute), Utrecht, The Netherlands.

出版信息

J Psychiatr Res. 2018 Jul;102:132-135. doi: 10.1016/j.jpsychires.2018.04.001. Epub 2018 Apr 5.

DOI:10.1016/j.jpsychires.2018.04.001
PMID:29649722
Abstract

In a previous study (Van Ditzhuijzen et al., 2017) we investigated the incidence and recurrence of mental disorders 2.5 to 3 years post-abortion. The aim of the current study was to extend these findings with longer term follow up data, up until 5-6 years post-abortion. We compared data of women who had had an abortion of the Dutch Abortion and Mental Health Study (DAMHS) to women who did not have an abortion from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2) (N = 2227). We used 1-to-1 matching on background confounding variables and measured post-abortion incidence and recurrence of common DSM-IV mental disorders (mood, anxiety, and substance use disorders) using the Composite International Diagnostic Interview (CIDI) version 3.0. After matching on confounding variables, abortion did not increase the likelihood that women had incident or recurrent mental disorders in the 5-6 years post-abortion (any incident mental disorder: OR = 3.66, p = .16; any recurrent mental disorder: OR = 0.22, p = .47). We found no evidence that experiencing an abortion increases the risk on new or recurrent mental disorders on the longer term.

摘要

在之前的一项研究(Van Ditzhuijzen 等人,2017 年)中,我们调查了人工流产后 2.5 至 3 年期间精神障碍的发生率和复发率。本研究的目的是通过更长时间的随访数据(直至人工流产后 5-6 年)来扩展这些发现。我们将荷兰人工流产与心理健康研究(DAMHS)中进行过人工流产的女性的数据与荷兰心理健康调查和发病率研究-2(NEMESIS-2)中未进行人工流产的女性的数据进行了比较(N=2227)。我们使用背景混杂变量的 1:1 匹配,并使用复合国际诊断访谈(CIDI)第 3.0 版测量了人工流产后 5-6 年内常见 DSM-IV 精神障碍(情绪、焦虑和物质使用障碍)的发生率和复发率。在对混杂变量进行匹配后,人工流产并不会增加女性在人工流产后 5-6 年内发生或复发精神障碍的可能性(任何新发精神障碍:OR=3.66,p=.16;任何复发精神障碍:OR=0.22,p=.47)。我们没有发现证据表明人工流产会增加新的或复发的精神障碍的风险。

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