Cliniques Universitaires St. Luc, Renal Unit, Brussels, Belgium.
Charles University Medical School 1, Institute of Biophysics, Prague, Czech Republic.
Blood Purif. 2018;46(1):27-33. doi: 10.1159/000484921. Epub 2018 Apr 12.
Dialysate conductivity is routinely used as a surrogate for dialysate sodium concentration. However, dialysis machine manufacturers apply different conductivity temperature correction coefficients. With the same conductivity in dialysis machines manufactured by different manufacturers, dialysate sodium may significantly differ. Also, electrolyte prescriptions are individualized (K, Ca, HCO3) and this is associated with another variation in dialysate sodium in the order of 1-5 mmol/L and both deviations are cumulative and chronic for each patient. Equivalence of the prescribed dialysate sodium and the concentration measured in it is not granted. Both variables differ and it is machine dependent! This paper analyses those variations from a technical point of view and suggests how to detect them and how to deal with or avoid them in clinical practice.
透析液电导率通常被用作透析液钠浓度的替代物。然而，透析机制造商采用不同的电导率温度校正系数。即使在不同制造商生产的透析机中电导率相同，透析液钠也可能有显著差异。此外，电解质处方是个体化的（K、Ca、HCO3），这与透析液钠的另一个变化有关，范围在 1-5mmol/L 之间，并且这些偏差对每个患者来说都是累积和慢性的。所规定的透析液钠与实际测量浓度之间的等效性是无法保证的。这两个变量存在差异，而且是由机器决定的！本文从技术角度分析了这些变化，并提出了如何检测它们，以及如何在临床实践中处理或避免这些变化。
