1 Department of Urology, Guangdong Key Laboratory of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University , Guangzhou, China .
2 Department of Urology, Kashgar Prefecture First People's Hospital of Kashi , Xinjiang, China .
J Endourol. 2018 Jun;32(6):465-470. doi: 10.1089/end.2017.0860. Epub 2018 May 14.
To analyze urinary stone compositions in patients from Kashgar, China.
We analyzed the components of urinary stones in 732 consecutive patients with urolithiasis admitted to the First and Second People's Hospital of Kashgar Prefecture, Xinjiang, from July 2014 to November 2016. The patients were divided into two groups by ages: group A, 0 to 18 years and group B, >18 years old. The distributions of various stone compositions were analyzed and correlated with the gender and age.
The mean age of group A was 3.90 ± 4.09 years and that of group B was 39.88 ± 16.40 years. The overall gender ratio (male:female) was 2.27:1. Ammonium acid urate (AAU) stone was the most frequent stone, male 35.83% and female 33.48%. Female patients were significantly more common than male patients in calcium apatite stone (p = 0.004). Of all 732 cases, patients younger than 18 years were more than patients older than 18 years (58.47% vs 41.53%). The majority of the patients (77.87%) had the stone located in the upper urinary tract. Two peak ages for both genders were noted in 1 to 3 years and 19 to 40 years group of the patients. In group of 1 to 3 years patients, male were more than female (37.60% vs 24.55%, p = 0.001), whereas in the group of 10 to 18 years patients, female were more than male (10.71% vs 4.13%). AAU was the predominant stone component in group <1 year (70. 5%, p < 0.01, as compared with other groups.). Uric acid stone was more prevalent in group >60 years (66.8%, p < 0.01) than in other groups. Patients in 1 to 3 years were in the peak age group of AAU stones in both the upper and lower urinary tract.
Most of the patients with urolithiasis diagnosed and treated in Kashgar are <18 years old, especially younger than 3 years old. The most frequent stone component in this area was AAU. More than 50% patients <18 years old had AAU stone. The mechanisms that could trigger the high prevalence of AAU stone in patients <18 years old are worth further investigation.
分析中国喀什地区患者的尿石成分。
我们分析了 2014 年 7 月至 2016 年 11 月期间喀什地区第一人民医院和第二人民医院收治的 732 例尿石症患者的尿石成分。患者按年龄分为两组：A 组，0-18 岁；B 组，>18 岁。分析各种结石成分的分布，并与性别和年龄相关联。
A 组平均年龄为 3.90±4.09 岁，B 组为 39.88±16.40 岁。总体性别比（男：女）为 2.27:1。尿酸铵结石（AAU）是最常见的结石，男性占 35.83%，女性占 33.48%。女性患者的磷酸钙结石明显多于男性（p=0.004）。在所有 732 例患者中，18 岁以下的患者多于 18 岁以上的患者（58.47% vs 41.53%）。大多数患者（77.87%）的结石位于上尿路。两个年龄段在 1 至 3 岁和 19 至 40 岁的患者中都有出现。在 1 至 3 岁的患者中，男性多于女性（37.60% vs 24.55%，p=0.001），而在 10 至 18 岁的患者中，女性多于男性（10.71% vs 4.13%）。AAU 是 1 岁以下患者中主要的结石成分（70.5%，p<0.01，与其他组相比）。尿酸结石在>60 岁的患者中更为常见（66.8%，p<0.01）。1 至 3 岁的患者在上尿路和下尿路均处于 AAU 结石的高发年龄段。
在喀什诊断和治疗的尿石症患者中，大多数为<18 岁，尤其是<3 岁。该地区最常见的结石成分是 AAU。50%以上<18 岁的患者有 AAU 结石。<18 岁患者 AAU 结石高发的机制值得进一步研究。
