Nakao Eiichiro, Ozawa Rie, Takii Mamiko, Kaibe Nobuaki, Kurahashi Yasunori, Oshima Tsutomu, Niwa Hirotaka, Kikuchi Shojiro, Sasako Mitsuru, Shinohara Hisashi
Dept. of Upper Gastrointestinal Surgery, Hyogo College of Medicine.
Gan To Kagaku Ryoho. 2018 Apr;45(4):667-669.
We report a case of Stage IV gastric cancer showing pathological complete response(pCR)after neo-adjuvant chemotherapy( NAC)using S-1 and oxaliplatin(SOX).A woman 73-year-old was diagnosed as harming type 3 Stage IV gastric cancer with para-aortic lymph node(PAN)metastasis.She underwent 4 courses of NAC with SOX regimen.After the treatment, both the primary tumor and the metastatic PAN decreased in size remarkably.She underwent distal gastrectomy with D2 plus PAN dissection with curative intent.Pathological diagnosis revealed complete disappearance of cancer cells in both the primary lesion of the stomach and all dissected lymph nodes, confirming pCR.She is alive without recurrence 4 months after surgery.
我们报告一例IV期胃癌患者，其在使用S-1和奥沙利铂（SOX）进行新辅助化疗（NAC）后出现病理完全缓解（pCR）。一名73岁女性被诊断为伴有主动脉旁淋巴结（PAN）转移的3型IV期胃癌。她接受了4个疗程的SOX方案NAC治疗。治疗后，原发肿瘤和转移的PAN大小均显著减小。她接受了根治性远端胃切除术及D2淋巴结清扫加PAN清扫术。病理诊断显示胃原发灶和所有清扫淋巴结中的癌细胞均完全消失，证实为pCR。术后4个月，她仍存活且无复发。
