[S-1与奥沙利铂术前化疗（SOX疗法）治疗伴有主动脉旁淋巴结转移的晚期胃癌患者的病理完全缓解]
[Pathological Complete Response in a Case of Advanced Gastric Cancer with Para-Aortic Lymph Nodes Metastasis Treated by Preoperative Chemotherapy with S-1 and Oxaliplatin(SOX Therapy)].
作者信息
Noro Hiroshi, Hirao Takafumi, Takayama Keita, Hara Shuichiro, Yoshida Masayuki, Yoneda Kazuhiro, Ohashi Tomofumi, Osawa Hideki, Sakai Kenji, Ide Yoshito, Iwasaki Teruo, Hatanaka Nobutaka, Yamasaki Yoshio, Yoshida Yasuyuki
机构信息
Dept. of Surgery, Japan Community Health care Organization(JCHO)Osaka Hospital.
出版信息
Gan To Kagaku Ryoho. 2020 Dec;47(13):2278-2280.
The patient was a 73-year-old man, diagnosed as advanced gastric cancer with para-aortic lymph nodes(PAN)metastasis. He was treated by 3 courses of neoadjuvant chemotherapy(NAC)with S-1 and oxaliplatin(SOX therapy). CT showed significant reduction of both primary tumor and metastatic lymph nodes. We performed distal gastrectomy with D2 plus PAN dissection. The histopathological findings showed no residual viable tumor cell. The pathological effect of chemotherapy was judged Grade 3(pCR)in both primary tumor and dissected lymph nodes. He is alive without recurrence 21 months after surgery.
该患者为一名73岁男性，被诊断为伴有腹主动脉旁淋巴结（PAN）转移的晚期胃癌。他接受了3个疗程的以替吉奥（S-1）和奥沙利铂（SOX疗法）的新辅助化疗（NAC）。CT显示原发肿瘤和转移淋巴结均显著缩小。我们实施了D2根治术加PAN清扫的远端胃切除术。组织病理学检查结果显示无残留存活肿瘤细胞。原发肿瘤和清扫淋巴结的化疗病理效果均判定为3级（pCR）。术后21个月他仍存活且无复发。
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