Correlation between CHADS-VASc Score and Glaucoma Treatment and Prognosis.

PURPOSE

To find if CHADS-VASc scale can accurately predict the treatment, prognosis, and outcome for primary open-angle glaucoma (POAG).

PATIENTS AND METHODS

A survey of 250,000 patient years was taken, using the records of the Ophthalmology Department at Ziv Medical Center. Data was collected regarding the retinal nerve fiber layer (RNFL), visual field (VF), line of treatment (LOT) of glaucoma, and all the data needed to accurately calculate CHADS-VASc score for each patient.

RESULTS

Sixty-seven patients were included in the statistical analysis. The mean age was 72.5 years. The mean CHADS-VASc score was 3.27 + -1.7. Positive Pearson's correlation coefficients were found for LOT and CHADS-VASc score, 0.35, and for RNFL grade and CHA2DS2-VASc score, 0.37. The correlation was negative for RNFL width and CHA2DS2-VASc score, -0.35.

CONCLUSIONS

CHADS-VASc score was shown to be correlated with glaucoma. This correlation was manifested positively by the LOT needed to stop glaucoma progression, with higher CHADS-VASc scores correlated with more aggressive treatment. Since glaucoma is a disease with a progressing nature, it is important to treat patients aggressively on one hand, while offering the most benign treatment as possible on the other hand. Modification of the CHADS-VASc score could achieve an even higher correlation.