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氯胺酮在急诊科的作用不断扩大。

The Expanding Role of Ketamine in the Emergency Department.

机构信息

Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville, 655 West 8th Street, Jacksonville, FL, 32209, USA.

出版信息

Drugs. 2018 May;78(7):727-735. doi: 10.1007/s40265-018-0904-8.

DOI:10.1007/s40265-018-0904-8
PMID:29651740
Abstract

Patients frequently come to the emergency department for pain. For decades, ketamine has been used in the emergency department for procedural sedation but is now receiving attention as a potential alternative to opioids because of its unique analgesic effects. Additionally, ketamine's dissociative properties have made it a popular choice for sedating profoundly agitated patients. In this narrative review, these new roles for ketamine in the emergency department are discussed.

摘要

患者经常因疼痛到急诊科就诊。几十年来,氯胺酮一直被用于急诊科的程序性镇静,但由于其独特的镇痛作用,现在正作为阿片类药物的潜在替代品受到关注。此外,氯胺酮的分离特性使其成为镇静极度激动患者的热门选择。在这篇叙述性综述中,讨论了氯胺酮在急诊科的这些新作用。

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The Expanding Role of Ketamine in the Emergency Department.氯胺酮在急诊科的作用不断扩大。
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Chronification of Pain: Mechanisms, Current Understanding, and Clinical Implications.疼痛的慢性化:机制、当前认识和临床意义。
Curr Pain Headache Rep. 2018 Feb 5;22(2):9. doi: 10.1007/s11916-018-0666-8.
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J Opioid Manag. 2017 Mar/Apr;13(2):95-103. doi: 10.5055/jom.2017.0373.
3
A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.
优化氯胺酮的使用以减少因肿瘤原因行乳房切除术的女性的慢性术后疼痛:KALPAS 多中心随机对照试验的研究方案。
Trials. 2024 Jan 19;25(1):67. doi: 10.1186/s13063-023-07884-y.
4
Recent advances in the study of anesthesia-and analgesia-related mechanisms of S-ketamine.S-氯胺酮麻醉与镇痛相关机制的研究进展
Front Pharmacol. 2023 Sep 14;14:1228895. doi: 10.3389/fphar.2023.1228895. eCollection 2023.
5
Narrative Review: Low-Dose Ketamine for Pain Management.叙述性综述:低剂量氯胺酮用于疼痛管理
J Clin Med. 2023 May 2;12(9):3256. doi: 10.3390/jcm12093256.
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Single-Dose of Postoperative Ketamine for Postoperative Pain After Mastectomy: A Pilot Randomized Controlled Trial.单剂量术后氯胺酮用于乳房切除术后疼痛:一项试点随机对照试验。
J Pain Res. 2023 Mar 14;16:881-892. doi: 10.2147/JPR.S389564. eCollection 2023.
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Cureus. 2021 Dec 2;13(12):e20114. doi: 10.7759/cureus.20114. eCollection 2021 Dec.
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J Am Coll Emerg Physicians Open. 2020 Mar 10;1(3):183-189. doi: 10.1002/emp2.12023. eCollection 2020 Jun.
一项前瞻性随机双盲试验,比较静脉推注低剂量氯胺酮与短时间输注低剂量氯胺酮用于急诊科疼痛治疗的效果。
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