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Teaching a Young Dog New Tricks: Modifications to the Post-Transplantation Cyclophosphamide Haploidentical Transplantation Platform.

作者信息

Kanakry Christopher G, Luznik Leo

机构信息

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

出版信息

Biol Blood Marrow Transplant. 2018 Jun;24(6):1108-1110. doi: 10.1016/j.bbmt.2018.04.004. Epub 2018 Apr 10.

DOI:10.1016/j.bbmt.2018.04.004
PMID:29653207
Abstract
摘要

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2
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Impact of HLA Disparity in Haploidentical Bone Marrow Transplantation Followed by High-Dose Cyclophosphamide.HLA 不合的单倍体造血干细胞移植后序贯高剂量环磷酰胺治疗的影响。
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引用本文的文献

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Efflux capacity and aldehyde dehydrogenase both contribute to CD8+ T-cell resistance to posttransplant cyclophosphamide.外排能力和醛脱氢酶均有助于 CD8+ T 细胞对移植后环磷酰胺的耐药性。
Blood Adv. 2022 Sep 13;6(17):4994-5008. doi: 10.1182/bloodadvances.2022006961.
2
Mechanisms of Graft-versus-Host Disease Prevention by Post-transplantation Cyclophosphamide: An Evolving Understanding.移植后环磷酰胺预防移植物抗宿主病的机制:不断发展的认识。
Front Immunol. 2019 Nov 29;10:2668. doi: 10.3389/fimmu.2019.02668. eCollection 2019.
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Posttransplant cyclophosphamide vs cyclosporin A and methotrexate as GVHD prophylaxis in matched sibling transplantation.
移植后环磷酰胺与环孢素 A 和甲氨蝶呤预防同胞供者移植后移植物抗宿主病。
Blood Adv. 2019 Nov 12;3(21):3351-3359. doi: 10.1182/bloodadvances.2019000236.
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Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation.MHC单倍型相同小鼠造血细胞移植中移植后环磷酰胺的优化时机
Biol Blood Marrow Transplant. 2020 Feb;26(2):230-241. doi: 10.1016/j.bbmt.2019.09.030. Epub 2019 Oct 2.
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Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.移植后环磷酰胺通过诱导同种反应性 T 细胞功能障碍和抑制来预防移植物抗宿主病。
J Clin Invest. 2019 Mar 26;129(6):2357-2373. doi: 10.1172/JCI124218.