Suppr超能文献

动态股薄肌成形术治疗肛门直肠畸形患者持续性大便失禁的长期疗效

Long-Term Outcome after Dynamic Graciloplasty for Treatment of Persistent Fecal Incontinence in Patients with Anorectal Malformations.

作者信息

Danielson Johan, Karlbom Urban, Wester Tomas, Graf Wilhelm

机构信息

Barnkirurgiska Kliniken, Uppsala Universitet Institutionen for Kvinnors Och Barns Halsa, Uppsala, Sweden.

Department of Surgery, Uppsala Universitet Institutionen for Kirurgiska Vetenskaper, Uppsala, Sweden.

出版信息

Eur J Pediatr Surg. 2019 Jun;29(3):276-281. doi: 10.1055/s-0038-1641599. Epub 2018 Apr 13.

Abstract

PURPOSE

Dynamic graciloplasty (DGP) has been used to treat severe fecal incontinence since the 1980s. Previous studies have shown an inferior outcome in patients with anorectal malformations (ARMs). Our experience has been that DGP has been appreciated by ARM -patients. The objective of the study was to evaluate the long-term outcome of DGP in our patients with ARM compared with patients with other underlying conditions.

MATERIALS AND METHODS

Twenty-three patients operated with DGP at our institution from 1996 to 2010 were sent validated bowel function and quality of life questionnaires. Eighteen of 23 responded. Seven had ARM and 11 had other etiologies of fecal incontinence. The mean follow-up time was 11.6 years (range, 5-17).

RESULTS

Four of 7 of the patients with ARM and 8 of 11 of patients with other etiologies used their implants at follow-up. The Miller incontinence score was slightly higher for patients with ARMs, but they had less constipation and higher Fecal Incontinence Quality of Life (FIQL)- and 36-Item Short Form Health Survey (SF-36) scores. None of the differences were statistically significant.

CONCLUSION

This study cannot confirm earlier reports in which DGP has an inferior outcome in patients with ARM. We therefore believe that the procedure should remain a treatment option for selected patients.

摘要

目的

自20世纪80年代以来,动态股薄肌成形术(DGP)一直用于治疗严重大便失禁。既往研究表明,该手术在肛门直肠畸形(ARM)患者中的疗效较差。但我们的经验是,DGP受到ARM患者的认可。本研究的目的是评估DGP在我院ARM患者中的长期疗效,并与其他潜在疾病患者进行比较。

材料与方法

1996年至2010年在我院接受DGP手术的23例患者收到了经过验证的肠道功能和生活质量问卷。23例中有18例作出回应。其中7例患有ARM,11例有其他大便失禁病因。平均随访时间为11.6年(范围5 - 17年)。

结果

随访时,7例ARM患者中有4例、11例其他病因患者中有8例使用了植入物。ARM患者的米勒失禁评分略高,但便秘较少,大便失禁生活质量(FIQL)和36项简明健康调查(SF - 36)评分较高。这些差异均无统计学意义。

结论

本研究无法证实既往报道中DGP在ARM患者中疗效较差的观点。因此,我们认为该手术仍应作为特定患者的一种治疗选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验