Devinck F, Deveaux C, Bennis Y, Deken-Delannoy V, Jeanne M, Martinot-Duquennoy V, Guerreschi P, Pasquesoone L
Service de chirurgie plastique, reconstructrice et esthétique, centre de traitement des brûlures, hôpital R. Salengro, CHU de Lille, 59000 Lille, France.
Service de chirurgie plastique, reconstructrice et esthétique, centre de traitement des brûlures, hôpital R. Salengro, CHU de Lille, 59000 Lille, France.
Ann Chir Plast Esthet. 2018 Jun;63(3):191-196. doi: 10.1016/j.anplas.2018.03.008. Epub 2018 Apr 10.
Chemical burns are rare but often lead to deep cutaneous lesions. Alkali agents have a deep and long lasting penetrating power, causing burns that evolve over several days. The local treatment for these patients is excision of the wound and split thickness skin graft. Early excision and immediate skin grafting of alkali burns are more likely to be complicated by graft failure and delayed wound healing. We propose a two-step method that delays skin grafting until two-three days after burn wound excision.
Our population included 25 controls and 16 cases. Men were predominant with a mean age of 41.9 years. In 78% of cases, burns were located on the lower limbs. The mean delay between the burn and excision was 16.5 days. In cases, the skin graft was performed at a mean of 11.3 days after the initial excision. We did not unveil any significant difference between both groups for the total skin surface affected, topography of the burns and the causal agent. Wound healing was significantly shorter in cases vs controls (37.5 days vs 50.3 days; P<0.025). Furthermore, we observed a decreased number of graft failures in cases vs controls (13.3% vs 46.7%; P=0.059).
Our study shows the relevance of a two-step surgical strategy in patients with alkali chemical burns. Early excision followed by interval skin grafting is associated with quicker wound healing and decreased rate of graft failure.
化学烧伤较为罕见,但常导致深度皮肤损伤。碱性制剂具有深层且持久的穿透力,会引起数天内逐渐发展的烧伤。这些患者的局部治疗方法是伤口切除和中厚皮片移植。碱烧伤的早期切除并立即进行皮肤移植更易出现移植失败和伤口愈合延迟等并发症。我们提出一种两步法,将皮肤移植推迟至烧伤伤口切除后两到三天进行。
我们的研究对象包括25名对照者和16例患者。男性居多,平均年龄为41.9岁。78%的病例烧伤位于下肢。烧伤与切除之间的平均间隔时间为16.5天。在病例组中,皮肤移植平均在初次切除后11.3天进行。我们未发现两组在受影响的皮肤总面积、烧伤部位和致伤因素方面存在任何显著差异。病例组的伤口愈合时间明显短于对照组(37.5天对50.3天;P<0.025)。此外,我们观察到病例组的移植失败数量低于对照组(13.3%对46.7%;P=0.059)。
我们的研究表明两步手术策略对碱化学烧伤患者具有重要意义。早期切除后间隔进行皮肤移植与更快的伤口愈合及降低的移植失败率相关。