Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK.
Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, UK; Department of Vascular Surgery, Oxford University Hospitals NHS Foundation Trust, UK.
Eur J Vasc Endovasc Surg. 2018 Aug;56(2):271-281. doi: 10.1016/j.ejvs.2018.03.007. Epub 2018 Apr 11.
OBJECTIVE/BACKGROUND: There are few published data on the acute care or long-term costs after acute/critical limb or visceral ischaemia (ACLVI) events. Using data from patients with acute events in a population based incidence study (Oxford Vascular Study), the present study aimed to determine the long-term costs after an ACLVI event.
All patients with first ever incident ACLVI from 2002 to 2012 were included. Analysis was based on follow up until January 2017, with all patients having full 5 year follow up. Multivariate regressions were used to assess baseline and subsequent predictors of total 5 year hospital care costs. Overall costs after an ACLVI event were benchmarked against those after stroke in the same population, during the same period.
Among 351 patients with an ACLVI event, mean 5 year total care costs were €35,211 (SD 50,500), of which €6443 (18%) were due to long-term institutionalisation. Costs differed by type of event (acute visceral ischaemia €16,476; acute limb ischaemia €24,437; critical limb ischaemia €46,281; p < 0.001). Results of the multivariate analyses showed that patients with diabetes and those undergoing above knee amputations incurred additional costs of €11,804 (p = 0.014) and €25,692 (p < 0.001), respectively. Five year hospital care costs after an ACLVI event were significantly higher than after stroke (€28,768 vs. €22,623; p = 0.004), but similar after including long-term costs of institutionalisation (€35,211 vs. €35,391; p = 0.957).
Long-term care costs after an ACLVI event are considerable, especially after critical limb ischaemia. Hospital care costs were significantly higher than for stroke over the long term, and were similar after inclusion of costs of institutionalisation.
目的/背景:急性/重症肢体或内脏缺血(ACLVI)事件后,急性护理或长期成本的相关数据很少。本研究利用一项基于人群的发病研究(牛津血管研究)中急性发病患者的数据,旨在确定 ACLVI 事件后的长期成本。
纳入 2002 年至 2012 年首次发生 ACLVI 的所有患者。分析基于 2017 年 1 月前的随访情况,所有患者均进行了 5 年的完整随访。采用多元回归分析评估 ACLVI 事件后 5 年内总住院护理费用的基线和后续预测因素。将 ACLVI 事件后的总费用与同一人群中同一时期的中风进行基准比较。
在 351 例 ACLVI 患者中,5 年总护理费用平均为 35211 欧元(50500 欧元),其中 6443 欧元(18%)是由于长期住院治疗所致。不同类型的事件费用不同(急性内脏缺血 €16476;急性肢体缺血 €24437;重症肢体缺血 €46281;p<0.001)。多元分析结果显示,患有糖尿病和接受膝上截肢的患者分别增加了 11804 欧元(p=0.014)和 25692 欧元(p<0.001)的费用。ACLVI 事件后 5 年的住院护理费用明显高于中风(€28768 比 €22623;p=0.004),但包括长期住院费用后相似(€35211 比 €35391;p=0.957)。
ACLVI 事件后长期护理费用相当可观,尤其是重症肢体缺血后。长期来看,医院护理费用明显高于中风,包括长期住院费用后两者相似。