在巴西南部，一名患者在佩戴隐形眼镜游泳后感染了导致角膜炎的强毒力T4型棘阿米巴。
Virulent T4 Acanthamoeba causing keratitis in a patient after swimming while wearing contact lenses in Southern Brazil.
作者信息
Fabres Laura Fuhrich, Maschio Vinicius José, Santos Denise Leal Dos, Kwitko Sergio, Marinho Diane Ruschel, Araújo Bruno Schneider de, Locatelli Claudete Inês, Rott Marilise Brittes
机构信息
Department of Microbiology, Immunology and Parasitology, Institute of Basic Health Sciences, Division of Parasitology, Universidade Federal do Rio Grande do Sul, Sarmento Leite Street, N 500, Porto Alegre, Rio Grande do Sul, 90050-170, Brazil.
Cornea Division, Department of Ophthalmology, Hospital de Clínicas de Porto Alegre, Rio Grande do Sul, Ramiro Barcelos Street, N 2350, Porto Alegre, Rio Grande do Sul, 90035-903, Brazil.
出版信息
Acta Parasitol. 2018 Jun 26;63(2):428-432. doi: 10.1515/ap-2018-0050.
Several strains of free-living amoebae belonging to the genus Acanthamoeba can cause a painful sight-threatening disease of the cornea known as Acanthamoeba keratitis (AK). The numbers of AK cases keep rising worldwide mainly due to an increase in contact lens wearers and lack of hygiene in the maintenance of contact lenses and their cases. We report a case of AK in a healthy young woman admitted to the Hospital de Clinicas in Porto Alegre, southern Brazil. Corneal scrapings were examined for the presence of Acanthamoeba strains. The initial isolate was characterized by morphological and genotypic properties. The isolate belonged to group III according to Pussard and Pons' cyst morphology. Analysis of its 18S rDNA sequence identified the isolate as genotype T4. The T4 genotype is the most commonly reported among keratitis isolates and the most common in environmental samples.
几种属于棘阿米巴属的自由生活阿米巴菌株可引起一种威胁视力的角膜疼痛性疾病，称为棘阿米巴角膜炎（AK）。全球范围内AK病例数持续上升，主要原因是隐形眼镜佩戴者增加以及隐形眼镜及其护理盒的维护缺乏卫生。我们报告了一例在巴西南部阿雷格里港临床医院住院的健康年轻女性患AK的病例。对角膜刮片进行检查以确定是否存在棘阿米巴菌株。最初的分离株通过形态学和基因型特性进行表征。根据Pussard和Pons的囊肿形态，该分离株属于III组。对其18S rDNA序列的分析确定该分离株为T4基因型。T4基因型是角膜炎分离株中最常报道的，也是环境样本中最常见的。
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