Suppr超能文献

慢性炎症性风湿病患者多种共病系统筛查的相关性和可行性。

Relevance and feasibility of a systematic screening of multimorbidities in patients with chronic inflammatory rheumatic diseases.

机构信息

Department of Rheumatology, CHU de Montpellier, 34000 Montpellier, France; Montpellier University, 34000 Montpellier, France; Institut de génétique moléculaire Montpellier, UMR5535, CNRS, 34000 Montpellier, France.

Department of Rheumatology, CHU de Montpellier, 34000 Montpellier, France; Montpellier University, 34000 Montpellier, France.

出版信息

Joint Bone Spine. 2019 Jan;86(1):49-54. doi: 10.1016/j.jbspin.2018.03.016. Epub 2018 Apr 11.

Abstract

OBJECTIVES

EULAR recently proposed to screen multimorbidities in chronic inflammatory rheumatic diseases. The aims of the study were to define the most common multimorbidities in chronic inflammatory rheumatic diseases, compare the screening approach performed in the clinic with the recent EULAR recommendations, validate the points to consider for the systematic standardized multimorbidity screening proposed by EULAR and assess feasibility of such a screening in a daily clinic.

METHODS

Data were collected prospectively during a 1-day multimorbidity clinic. Diabetes, hypertension, CVD damage, chronic respiratory diseases, osteoporosis and preventive measures were assessed. The comparison with EULAR points to consider was performed retrospectively.

RESULTS

We included 200 consecutive patients (157 with rheumatoid arthritis, 37 spondyloarthritis, and 6 connective tissue diseases or vasculitis). The most common multimorbidities already diagnosed in our patients were hypertension (26%) and diabetes (7.5%). Screening showed that 61.5% (CI95%: 54.6%-67.9%) patients presented at least one undiagnosed or uncontrolled diseases: diabetes (6%), hypertension (20.6%), dyslipidemia (16.1%) valvulopathies (16.8%), peripheral artery disease (4.5%); carotid stenosis (6.5%) and aortic aneurysm (5.5%). Overall, 39.9% patients had incomplete cancer screening and 52.8% incomplete vaccine schedule. Undiagnosed pulmonary obstruction and risk of sleep apnea were suspected in 15.5% and 40.1% patients, respectively.

CONCLUSION

This study underlines the relevance of a systematic screening of multimorbidities in chronic inflammatory rheumatic diseases and its feasibility in a 1-day clinic. Spirometry and sleep apnea screening should be added to EULAR points to consider. The long-term impact of such screening needs to be evaluated.

摘要

目的

EULAR 最近提出在慢性炎症性风湿病中筛查多种合并症。本研究旨在确定慢性炎症性风湿病中最常见的多种合并症,比较在临床中进行的筛查方法与 EULAR 的最新建议,验证 EULAR 提出的系统性标准化多种合并症筛查的注意事项,并评估在日常临床中进行这种筛查的可行性。

方法

数据在 1 天的多种合并症诊所期间前瞻性收集。评估糖尿病、高血压、心血管疾病损伤、慢性呼吸系统疾病、骨质疏松症和预防措施。与 EULAR 注意事项进行回顾性比较。

结果

我们纳入了 200 例连续患者(157 例类风湿关节炎、37 例脊柱关节炎和 6 例结缔组织病或血管炎)。我们的患者中已经诊断出的最常见的多种合并症是高血压(26%)和糖尿病(7.5%)。筛查显示,61.5%(95%CI:54.6%-67.9%)的患者至少有一种未诊断或未控制的疾病:糖尿病(6%)、高血压(20.6%)、血脂异常(16.1%)、瓣膜病(16.8%)、外周动脉疾病(4.5%);颈动脉狭窄(6.5%)和主动脉瘤(5.5%)。总体而言,39.9%的患者癌症筛查不完全,52.8%的患者疫苗接种计划不完全。15.5%和 40.1%的患者分别怀疑存在未诊断的肺阻塞和睡眠呼吸暂停风险。

结论

本研究强调了在慢性炎症性风湿病中进行系统性多种合并症筛查的相关性及其在 1 天诊所中的可行性。应将肺功能检查和睡眠呼吸暂停筛查添加到 EULAR 注意事项中。需要评估这种筛查的长期影响。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验