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德国勃兰登堡州野生和家养食肉动物中戊型肝炎病毒的分子和血清学监测。

Molecular and serological surveillance of Hepatitis E virus in wild and domestic carnivores in Brandenburg, Germany.

机构信息

Institute of Novel and Emerging Infectious Diseases at the Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

Institute of Epidemiology at the Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

出版信息

Transbound Emerg Dis. 2018 Oct;65(5):1377-1380. doi: 10.1111/tbed.12877. Epub 2018 Apr 14.

DOI:10.1111/tbed.12877
PMID:29655214
Abstract

Hepatitis E virus (HEV) is a zoonotic virus which circulates in pigs and wild boars as main reservoir species. To reveal the infection rate in carnivores, we have carried out a monitoring study of raccoons, raccoon dogs, dogs and cats sampled in Brandenburg, Germany. In summary, 53.8% (43 of 80) of the raccoons, 34.3% (25 of 73) of the raccoon dogs, 56.6% (47 of 83) of dogs and 32.3% (21 of 65) of cats were tested positive for HEV-specific antibodies. No viral RNA could be detected. This first description of anti-HEV antibodies in raccoons and raccoon dogs worldwide and in dogs and cats in Germany highlights the natural host range expansion of HEV.

摘要

戊型肝炎病毒 (HEV) 是一种动物源性病毒,主要在猪和野猪中循环。为了揭示肉食动物的感染率,我们对德国勃兰登堡州的浣熊、貉、狗和猫进行了监测研究。总之,80 只浣熊中有 53.8%(43 只)、73 只貉中有 34.3%(25 只)、83 只狗中有 56.6%(47 只)和 65 只猫中有 32.3%(21 只)被检测出抗 HEV 抗体呈阳性。未检测到病毒 RNA。这是全球范围内首次在浣熊和貉以及德国的狗和猫中描述抗 HEV 抗体,突显了 HEV 自然宿主范围的扩大。

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