Liang Qin-Li, Nie Lan-Bi, Zou Yang, Hou Jun-Ling, Chen Xiao-Qing, Bai Meng-Jie, Gao Yun-Hang, Hu Gui-Xue, Zhu Xing-Quan
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, People's Republic of China; College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin Province 130118, People's Republic of China.
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, People's Republic of China.
Acta Trop. 2019 Apr;192:87-90. doi: 10.1016/j.actatropica.2019.02.004. Epub 2019 Feb 6.
Hepatitis E virus (HEV) and influenza A virus (IAV) are two important pathogens which can infect humans and various animals causing public health problems. In this study, the seroprevalence and risk factors associated with HEV and IAV infection in farmed wild boars were investigated in China. A total of 758 serum samples were collected from farmed wild boars between 2015 and 2016, and antibodies against HEV and IAV were examined by enzyme-linked immunosorbent assay (ELISA) using commercially available kits. The overall prevalence of anti-HEV antibodies was 24.54% (186/758, 95% CI 21.48-27.60) in farmed wild boars. There were statistically significant differences in the HEV seroprevalence in farmed wild boars of different ages (<22 days: 8.33%; 22-66 days: 18.89%; >66 days: 26.36%) (P < 0.05) and different genders (50.00% in male and 23.49% in female) (P < 0.01). However, there was no statistically significant difference in the HEV seroprevalence in farmed wild boars of different regions and different years. The overall IAV seroprevalence was 5.80% (44/758, 95% CI 4.14-7.46), and there was no statistically significant difference in the IAV seroprevalence in farmed wild boars of different ages and genders, collected from different regions and different years. Our results indicate that HEV and IAV infections in farmed wild boars may pose a potential risk for human infection. To our knowledge, this is the first report of HEV and IAV seroprevalence in farmed wild boars in China, which provides baseline data for further studies and for control of HEV and IAV infection in farmed wild boars.
戊型肝炎病毒（HEV）和甲型流感病毒（IAV）是两种重要的病原体，可感染人类和多种动物，引发公共卫生问题。本研究在中国调查了养殖野猪中与HEV和IAV感染相关的血清流行率及危险因素。2015年至2016年期间，共采集了758份养殖野猪的血清样本，并使用市售试剂盒通过酶联免疫吸附测定（ELISA）检测了抗HEV和抗IAV抗体。养殖野猪中抗HEV抗体的总体流行率为24.54%（186/758，95%置信区间21.48 - 27.60）。不同年龄（<22天：8.33%；22 - 66天：18.89%；>66天：26.36%）和不同性别的养殖野猪中HEV血清流行率存在统计学显著差异（P < 0.05）（雄性为50.00%，雌性为23.49%）（P < 0.01）。然而，不同地区和不同年份的养殖野猪中HEV血清流行率无统计学显著差异。IAV的总体血清流行率为5.80%（44/758，95%置信区间4.14 - 7.46），不同年龄、性别、地区和年份采集的养殖野猪中IAV血清流行率无统计学显著差异。我们的结果表明，养殖野猪中的HEV和IAV感染可能对人类感染构成潜在风险。据我们所知，这是中国养殖野猪中HEV和IAV血清流行率的首次报告，并为进一步研究以及控制养殖野猪中的HEV和IAV感染提供了基线数据。
