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桥小脑角区原发性中枢神经系统淋巴瘤误诊为三叉神经鞘瘤:1例独特病例报告及文献复习

Primary central nervous system lymphoma at the cerebellopontine angle mimicking a trigeminal schwannoma: A unique case report and literature review.

作者信息

Seevaratnam Vijay, Li Yingda, Lee Sun Loong Keegan, Olsson Gemma

机构信息

Department of Neurosurgery, Westmead Hospital, Hawkesbury Road Westmead, NSW 2145, Australia.

Department of Neurosurgery, Westmead Hospital, Hawkesbury Road Westmead, NSW 2145, Australia.

出版信息

J Clin Neurosci. 2018 Jun;52:115-119. doi: 10.1016/j.jocn.2018.01.016. Epub 2018 Apr 11.

Abstract

Primary central nervous system lymphoma (PCNSL) is an uncommon extranodal manifestation of non-Hodgkin's lymphoma with those presenting at the cerebellopontine angle (CPA) being rare presentations with limited reported cases in the literature. We report a 60-year old female presenting with PCNSL of the left CPA radiologically mimicking a trigeminal schwannoma with corresponding clinical signs. Imaging showed a left CPA lesion that was biopsied and confirmed as diffuse large B-cell lymphoma. Given its rarity, PCNSL should be considered in the differential diagnosis for all CPA tumours.

摘要

原发性中枢神经系统淋巴瘤(PCNSL)是非霍奇金淋巴瘤一种不常见的结外表现,而发生于桥小脑角(CPA)的病例较为罕见,文献报道的病例有限。我们报告一例60岁女性,其左侧CPA处的PCNSL在影像学上酷似三叉神经鞘瘤并伴有相应临床体征。影像学检查显示左侧CPA区有一病变,经活检确诊为弥漫性大B细胞淋巴瘤。鉴于其罕见性,所有CPA区肿瘤的鉴别诊断均应考虑PCNSL。

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