Holm-Pedersen P, Gaumer H R, Folke L E
Scand J Dent Res. 1979 Dec;87(6):431-4. doi: 10.1111/j.1600-0722.1979.tb00704.x.
The blastogenic response of peripheral blood leukocytes to lipopolysaccharide (LPS), phytohemagglutinin (PHA) and LPS/PHA mixtures was followed over a short course of experimental gingivitis in elderly subjects (65-81 years) who strictly avoided oral hygiene procedures for periods up to 9 d. The leukocytes responded poorly to LPS, PHA and to LPS/PHA combinations. The concomitant heightened sensitivity of the gingiva to dental plaque among the elderly subjects may relate to the altered leukocyte response in this age group.
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