Holm-Pedersen P, Gaumer H R, Folke L E
Scand J Dent Res. 1979 Dec;87(6):431-4. doi: 10.1111/j.1600-0722.1979.tb00704.x.
The blastogenic response of peripheral blood leukocytes to lipopolysaccharide (LPS), phytohemagglutinin (PHA) and LPS/PHA mixtures was followed over a short course of experimental gingivitis in elderly subjects (65-81 years) who strictly avoided oral hygiene procedures for periods up to 9 d. The leukocytes responded poorly to LPS, PHA and to LPS/PHA combinations. The concomitant heightened sensitivity of the gingiva to dental plaque among the elderly subjects may relate to the altered leukocyte response in this age group.
在老年受试者（65 - 81岁）短期实验性牙龈炎过程中，观察外周血白细胞对脂多糖（LPS）、植物血凝素（PHA）以及LPS/PHA混合物的增殖反应。这些老年受试者严格避免口腔卫生措施长达9天。白细胞对LPS、PHA以及LPS/PHA组合的反应较差。老年受试者牙龈对牙菌斑的敏感性同时增加，这可能与该年龄组白细胞反应改变有关。
