Vide Sérgio, Gambús Pedro L
Hospital CLINIC de Barcelona, Anesthesiology Department, Systems Pharmacology Effect Control & Modeling (SPEC-M) Research Group, Barcelona, Spain; Hospital Pedro Hispano, Department of Anesthesia, Matosinhos, Portugal; Centro Hospitalar Universitário do Porto, Department of Anesthesiology, Center for Clinical Research in Anesthesia, Porto, Portugal.
Hospital CLINIC de Barcelona, Anesthesiology Department, Systems Pharmacology Effect Control & Modeling (SPEC-M) Research Group, Barcelona, Spain; University of California San Francisco (UCSF), Department of Anesthesia and Perioperative Care, San Francisco, California, USA; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), NeuroImmunology Research Group, Barcelona, Spain.
Presse Med. 2018 Apr;47(4 Pt 2):e65-e72. doi: 10.1016/j.lpm.2018.03.010. Epub 2018 Apr 12.
Cognition is essential to all aspects of our everyday life. Although we take our cognitive function for granted, the perioperative period is prone to several aggressions that might impair it. Postoperative cognitive dysfunction, has been the aim of many studies recently, and was shown to be very common with an incidence that can reach 40%, yielding not only impairment in cognition, but also longer hospital stays, higher costs and greater mortality. While several studies have revealed some of the mechanisms contributing to postoperative cognitive dysfunction, the search for the perfect instrument to screen and measure cognitive (dys)function has proven more elusive. The present paper aims to review several cognitive evaluation methods, discussing their advantages and disadvantages as well as their potential clinical applications in evaluating the dynamics of the recovery of cognitive function after anesthesia and surgery. The current availability of easy to use computerized tests might provide the tools necessary to identify patients at risk, and promptly provide them with the adequate course of action.
认知对于我们日常生活的方方面面都至关重要。尽管我们对自己的认知功能习以为常，但围手术期容易受到多种可能损害认知功能的侵害。术后认知功能障碍是最近许多研究的目标，结果表明它非常常见，发病率可达40%，不仅会导致认知功能受损，还会延长住院时间、增加费用并提高死亡率。虽然多项研究揭示了一些导致术后认知功能障碍的机制，但寻找用于筛查和测量认知（功能）障碍的完美工具却更加困难。本文旨在综述几种认知评估方法，讨论它们的优缺点以及在评估麻醉和手术后认知功能恢复动态方面的潜在临床应用。当前易于使用的计算机化测试的可用性可能提供识别高危患者并及时为他们提供适当行动方案所需的工具。
