Department of Pediatric Surgery, Skåne University Hospital, Lund, Sweden; Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Department of Pediatric Surgery, Skåne University Hospital, Lund, Sweden; Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
J Pediatr. 2018 Jul;198:131-136.e2. doi: 10.1016/j.jpeds.2018.02.031. Epub 2018 Apr 12.
To evaluate urinary tract and bowel function in children with sacrococcygeal teratoma, compare the findings with healthy children, and assess predictors of poor outcome.
This was a controlled cohort study of all patients operated for sacrococcygeal teratoma at a tertiary pediatric surgery center, 2000-2013. Urinary and bowel function were compared with healthy control patients matched for age and sex. Perioperative and histopathologic risk factors were analyzed.
In total, 17 patients with sacrococcygeal teratoma and 85 healthy control patients were included in the study. Patients with sacrococcygeal teratoma more often were reported to have uncontrolled voiding (12% vs 0%, P < .01), difficulty in bladder emptying (24% vs 0%, P < .001), and pyelonephritis (18% vs 1%, P < .05). Constipation was more common in patients with sacrococcygeal teratoma (47 % vs 14%, P < .05), but the overall bowel function score was equal in the 2 groups. Children with large tumors and immature histology were more likely to have a dysfunctional outcome (P < .05).
Uncontrolled voiding, difficulty in bladder emptying, pyelonephritis, and constipation were more common in patients with sacrococcygeal teratoma than in healthy children. Dysfunctional outcome was more prevalent in children with large and immature teratomas.
评估骶尾部畸胎瘤患儿的尿路和肠道功能，将其与健康儿童的结果进行比较，并评估预后不良的预测因素。
这是一项在 2000 年至 2013 年在一家三级儿科手术中心对所有接受骶尾部畸胎瘤手术的患者进行的对照队列研究。将尿路和肠道功能与年龄和性别相匹配的健康对照患者进行比较。分析围手术期和组织病理学危险因素。
共纳入 17 例骶尾部畸胎瘤患儿和 85 例健康对照患儿。与健康对照组相比，患有骶尾部畸胎瘤的患儿更常出现无法控制的排尿（12% vs 0%，P <.01）、膀胱排空困难（24% vs 0%，P <.001）和肾盂肾炎（18% vs 1%，P <.05）。骶尾部畸胎瘤患儿更常出现便秘（47% vs 14%，P <.05），但两组的整体肠道功能评分相等。肿瘤较大和组织学不成熟的患儿更有可能出现功能障碍（P <.05）。
与健康儿童相比，骶尾部畸胎瘤患儿更常出现无法控制的排尿、膀胱排空困难、肾盂肾炎和便秘。较大和不成熟的畸胎瘤患儿更易出现功能障碍。
