Reinberg Y, Long R, Manivel J C, Resnick J, Simonton S, Gonzalez R
Department of Urologic Surgery, University of Minnesota, Minneapolis.
J Urol. 1993 Sep;150(3):948-9. doi: 10.1016/s0022-5347(17)35658-6.
Sacrococcygeal teratoma is the most common extragonadal germ cell tumor of infancy. Associated urological complications, most of which are reported in children with malignancy, include vesicoureteral reflux, ureteral and urethral obstruction, and neurogenic bladder. To evaluate the influence of tumor grade and type on adverse urological outcome we reviewed the charts of 29 children with sacrococcygeal teratoma and correlated urological problems to lesion type and grade. No correlation was noted between tumor grade and the incidence of urological complications. The most common urological complications were neurogenic bladder in 12% of the patients, ureteral obstruction in 10% and vesicoureteral reflux in 7%. The highest incidence of urological complications (81%) was seen in patients with type IV (presacral) disease. We recommend early radiographic and neurourodynamic evaluation in all children with sacrococcygeal teratoma.
骶尾部畸胎瘤是婴儿期最常见的性腺外生殖细胞肿瘤。相关的泌尿系统并发症，其中大多数在患有恶性肿瘤的儿童中报道，包括膀胱输尿管反流、输尿管和尿道梗阻以及神经源性膀胱。为了评估肿瘤分级和类型对不良泌尿系统结局的影响，我们回顾了29例骶尾部畸胎瘤患儿的病历，并将泌尿系统问题与病变类型和分级相关联。未发现肿瘤分级与泌尿系统并发症发生率之间存在相关性。最常见的泌尿系统并发症是12%的患者出现神经源性膀胱，10%出现输尿管梗阻，7%出现膀胱输尿管反流。IV型（骶前）疾病患者的泌尿系统并发症发生率最高（81%）。我们建议对所有骶尾部畸胎瘤患儿进行早期影像学和神经尿动力学评估。
