Awadallah Michael, Idle Matthew, Patel Ketan, Kademani Deepak
Department of Oral and Maxillofacial Surgery, North Memorial Medical Center, Minneapolis, MN, USA.
Department of Oral and Maxillofacial Surgery, North Memorial Medical Center, Minneapolis, MN, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jun;125(6):628-636. doi: 10.1016/j.oooo.2018.03.010. Epub 2018 Mar 23.
The term oral potentially malignant disorders, proposed at the World Health Organization workshop in 2005, has now been renamed potentially premalignant oral epithelial lesions (PPOELs). It is important to differentiate among PPOELs, which is a broad term to define a wide variety of clinical lesions, and oral epithelial dysplasia, which should be reserved specifically for lesions with biopsy-proven foci of dysplasia. PPOELs encompass lesions that include leukoplakia, erythroplakia, erythroleukoplakia, lichen planus, and oral submucous fibrosis. The primary goal of management of dysplasia includes prevention, early detection, and treatment before malignant transformation. The aim of this article is to inform the clinician about management of PPOELs.
“口腔潜在恶性疾病”这一术语于2005年在世界卫生组织研讨会上被提出，现在已更名为潜在恶性口腔上皮病变（PPOELs）。区分PPOELs（这是一个用于定义多种临床病变的宽泛术语）和口腔上皮发育异常很重要，口腔上皮发育异常应专门用于活检证实有发育异常灶的病变。PPOELs包括白斑、红斑、红白斑、扁平苔藓和口腔黏膜下纤维化等病变。发育异常的主要管理目标包括预防、早期检测以及在恶变前进行治疗。本文的目的是告知临床医生关于PPOELs的管理。
