Sharma Manjuri, Doley Prodip, Das Himanab Jyoti
Department of Nephrology, Guwahati Medical College and Hospital, Guwahati, Assam, India.
Saudi J Kidney Dis Transpl. 2018 Mar-Apr;29(2):409-413. doi: 10.4103/1319-2442.229297.
Chronic kidney disease (CKD) is one of the leading causes of chronic diseases globally, with rising incidence and prevalence. It is a major risk factor for cerebrovascular disease and coronary artery disease, which are the main causes of death in this population. The etiology of CKD is varied. This study was performed to evaluate the various etiologies of CKD among patients presenting to the Department of Nephrology, Guwahati Medical College, a tertiary referral center. A total of 5718 CKD patients were evaluated to identify the cause of CKD. The most common cause was found to be diabetes mellitus in 42.2%, followed by chronic glomerulonephritis in 21.4%, hypertension in 19.5%, obstructive uropathy in 6.9%, chronic interstitial nephritis in 3.6%, and autosomal dominant polycystic kidney disease in 1.5% of the patients. Nearly 2.7% of the patients had CKD of unknown etiology. Most of the common causes of CKD are potentially treatable and initiating appropriate treatment early may prevent the development of CKD or progression to end-stage renal disease.
慢性肾脏病（CKD）是全球慢性疾病的主要病因之一，其发病率和患病率呈上升趋势。它是脑血管疾病和冠状动脉疾病的主要危险因素，而这两种疾病是该人群的主要死因。CKD的病因多种多样。本研究旨在评估在三级转诊中心古瓦哈蒂医学院肾脏病科就诊的患者中CKD的各种病因。共对5718例CKD患者进行评估以确定CKD的病因。最常见的病因是糖尿病，占42.2%，其次是慢性肾小球肾炎，占21.4%，高血压占19.5%，梗阻性肾病占6.9%，慢性间质性肾炎占3.6%，常染色体显性多囊肾病占1.5%。近2.7%的患者CKD病因不明。CKD的大多数常见病因是潜在可治疗的，早期开始适当治疗可能会预防CKD的发生或发展为终末期肾病。
