Jordan Bertrand
UMR 7268 ADÉS, Aix-Marseille, Université/EFS/ CNRS; CoReBio PACA, case 901, Parc scientifique de Luminy, 13288 Marseille Cedex 09, France.
Med Sci (Paris). 2018 Apr;34(4):363-365. doi: 10.1051/medsci/20183404018. Epub 2018 Apr 16.
A recent publication describes a sophisticated "liquid biopsy" procedure that analyses both tumoral DNA and proteins present in peripheral blood to provide sensitive detection of different types of cancer. These results represent a significant advance, but they still fall short of the sensitivity and specificity required, and it seems unlikely that they could progress to a level at which screening of the (asymptomatic) general population would have a really favourable benefit to risk ratio.