Leung J Ks, Lam R Pk
Accident and Emergency Department, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
Emergency Medicine Unit, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
Hong Kong Med J. 2018 Apr;24(2):191-199. doi: 10.12809/hkmj176875.
Hyperbaric oxygen therapy is widely accepted as life-saving treatment for decompression illness. Yet its use in acute carbon monoxide poisoning has remained controversial because of inconsistent findings in clinical trials. Hyperbaric oxygen therapy has an adjunctive role in managing gas gangrene, necrotising soft-tissue infection, and crush injury, as supported by case series. Several cases have been reported in the literature detailing the use of hyperbaric oxygen therapy in patients with severe anaemia in whom blood transfusion is not possible. Today, use of hyperbaric oxygen therapy in Hong Kong is limited by low awareness among physicians and patients, a lack of service access, and inadequate hospital and critical care support for the existing non-hospital facility. The recent introduction of a hospital-based facility is expected to benefit more patients for whom hyperbaric oxygen therapy is appropriate. This article reviews the mechanistic basis of and emerging scientific evidence to support the use of hyperbaric oxygen therapy in a number of acute medical emergencies, as well as the past and future development of hyperbaric oxygen therapy in Hong Kong.
高压氧疗法被广泛认为是治疗减压病的救命疗法。然而,由于临床试验结果不一致,其在急性一氧化碳中毒中的应用一直存在争议。病例系列研究表明,高压氧疗法在气性坏疽、坏死性软组织感染和挤压伤的治疗中具有辅助作用。文献中报道了几例详细描述在无法进行输血的严重贫血患者中使用高压氧疗法的病例。如今,香港高压氧疗法的应用受到医生和患者认知度低、服务获取困难以及现有非医院设施缺乏医院和重症监护支持的限制。最近引入的基于医院的设施预计将使更多适合接受高压氧疗法的患者受益。本文回顾了支持在一些急性医疗紧急情况中使用高压氧疗法的机制基础和新出现的科学证据,以及香港高压氧疗法的过去和未来发展。