1 Department of Radiology, Xiangya Hospital, Central South University , Changsha , China.
2 Department of Imaging Diagnosis Center, Sun Yat-sen University Cancer Center , Guangzhou , China.
Dentomaxillofac Radiol. 2018 Jul;47(6):20170459. doi: 10.1259/dmfr.20170459. Epub 2018 Apr 23.
To analyze the clinicopathological features and the CT and MRI features of patients with paranasal sinus fibrosarcoma.
Seven patients with surgically and pathologically confirmed paranasal sinus fibrosarcoma were enrolled. Their CT and MRI data and imaging features were retrospectively analyzed in detail.
The study participants were two males and five females (median age, 43 years; range, 22-73 years). CT or MRI showed a well-defined (n = 5) or ill-defined (n = 2), irregular (n = 6) or oval (n = 1) mass, with heterogeneous (n = 7) density. The lesions were isointense (n = 4) or hypointense (n = 2) on T weighted images, and showed heterogeneous (n = 6) mild hypointensity on T weighted images. Expansive (n = 6) and osteolytic (n = 1) bone destruction were observed. The tumors showed marked heterogeneous delayed enhancement (n = 6) on contrast-enhanced MRI images.
Paranasal sinus fibrosarcomas should be included in the differential diagnosis when a sinonasal neoplasm appears as a well- or ill-defined unilateral large irregular mass with characteristic mild hypointensity on T weighted MR images and shows expansive or osteolytic bone destruction and a marked heterogeneous delayed contrast-enhancement pattern.
分析鼻窦纤维肉瘤患者的临床病理特征及 CT 和 MRI 特征。
纳入 7 例经手术和病理证实的鼻窦纤维肉瘤患者，详细回顾性分析其 CT 和 MRI 资料及影像学特征。
研究对象为 2 名男性和 5 名女性（中位年龄 43 岁；范围 22-73 岁）。CT 或 MRI 显示边界清楚（n = 5）或不清楚（n = 2）、不规则（n = 6）或椭圆形（n = 1）肿块，密度不均匀（n = 7）。病变在 T1 加权图像上呈等信号（n = 4）或低信号（n = 2），在 T2 加权图像上呈不均匀轻度低信号（n = 6）。观察到膨胀性（n = 6）和溶骨性（n = 1）骨破坏。肿瘤在对比增强 MRI 图像上呈明显不均匀延迟强化（n = 6）。
当鼻腔鼻窦肿瘤表现为单侧大不规则边界清楚或不清楚的肿块，T2 加权 MR 图像上具有特征性的轻度低信号，伴有膨胀性或溶骨性骨破坏及明显不均匀延迟强化模式时，应考虑鼻窦纤维肉瘤的鉴别诊断。
