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通过 FADOI-COMPLIMED 评分评估内科住院患者的复杂性。一种假设方法。

The complexity of patients hospitalized in Internal Medicine wards evaluated by FADOI-COMPLIMED score(s). A hypothetical approach.

机构信息

Department of Clinical Science and Community, Section of Medical Statistics, Biometry and Epidemiology, Faculty of Medicine and Surgery, University of Milan, Milan, Italy.

Research Department FADOI Foundation, Milan, Italy.

出版信息

PLoS One. 2018 Apr 16;13(4):e0195805. doi: 10.1371/journal.pone.0195805. eCollection 2018.

Abstract

OBJECTIVES

The aim of this study is to develop a new predictive model to measure complexity of patients in medical wards.

SETTING

29 Internal Medicine departments in Italy.

MATERIALS AND METHODS

The study cohort was made of 541 consecutive patients hospitalized for any cause, aged more than 40 years and with at least two chronic diseases. First, we applied a hierarchical cluster analysis and the principal component analysis (PCA) to a panel of questionnaires [comorbidity (Charlson, CIRS), clinical stability (MEWS), social frailty (Flugelman), cognitive dysfunction (SPSMQ), depression (5-item GDS), functional dependence (ADL, IADL, Barthel), risk of sore threats (Exton-Smith scale), nutrition (MNA), pain (NRPS), adherence to therapy (Morisky scale)], in order to select domains informative for the definition of complexity. The following step was to create the score(s) needed to quantify it.

RESULTS

Two main clusters were identified: the first includes 7 questionnaires whose common denominator is dependence and frailty, the second consists of 3 questionnaires representative of comorbidity. Globally, they account for about 70% of the total variance (55.2% and 13.8%, respectively). The first principal component was simplified in "Complimed Score 1" (CS1) as a recalibrated average between the Barthel Index and the Exton Smith score, whereas the second cluster was approximated to "Complimed Score 2" (CS2), by using the Charlson score only.

CONCLUSIONS

Complexity is a two-dimensional clinical phenomenon. The FADOI-Complimed Score(s) is a new tool useful for the routine evaluation of complexity in medical patients, simple to use and taking around 10 minutes to complete.

摘要

目的

本研究旨在开发一种新的预测模型,以衡量内科病房患者的复杂性。

设置

意大利 29 个内科病房。

材料和方法

研究队列由 541 名因任何原因住院的连续患者组成,年龄超过 40 岁,至少患有两种慢性病。首先,我们对一组问卷[合并症(Charlson、CIRS)、临床稳定性(MEWS)、社会脆弱性(Flugelman)、认知功能障碍(SPSMQ)、抑郁(5 项 GDS)、功能依赖(ADL、IADL、Barthel)、压疮风险(Exton-Smith 量表)、营养(MNA)、疼痛(NRPS)、治疗依从性(Morisky 量表)]进行层次聚类分析和主成分分析(PCA),以选择对复杂性定义有信息的域。下一步是创建量化所需的分数。

结果

确定了两个主要聚类:第一个聚类包含 7 个问卷,它们的共同点是依赖和脆弱性,第二个聚类由 3 个代表合并症的问卷组成。总体而言,它们占总方差的约 70%(分别为 55.2%和 13.8%)。第一主成分简化为“Complimed 评分 1”(CS1),作为 Barthel 指数和 Exton Smith 评分之间的重新校准平均值,而第二个聚类通过仅使用 Charlson 评分近似为“Complimed 评分 2”(CS2)。

结论

复杂性是一种二维临床现象。FADOI-Complimed 评分是一种用于常规评估内科患者复杂性的新工具,使用简单,大约需要 10 分钟完成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ccd/5901927/697251d1f454/pone.0195805.g001.jpg

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