Batur Muhammed, Seven Erbil, Tanrıkulu Merhamet, Ekin Selami, Tekin Serek, Yasar Tekin
Medical Faculty, Department of Ophthalmology, Yuzuncu Yıl University, Van, Turkey.
Medical Faculty, Department of Pulmonary Medicine, Yuzuncu Yil University, Van, Turkey.
Clin Respir J. 2018 Jul;12(7):2271-2276. doi: 10.1111/crj.12903. Epub 2018 May 15.
It is well-known that pseudoexfoliative material deteriorates iris dilatation function. This material was also found in lung tissue. The aim of the study was to evaluate pulmonary function in patients with pseudoexfoliation.
This prospective study included 60 pseudoexfoliation syndrome patients without any pulmonary diseases and 52 age- and gender-matched controls without any pulmonary diseases. Patients were asked about their cigarette use and the presence of any systemic diseases such as diabetes mellitus, arterial hypertension and asthma. All cases underwent full ophthalmologic and general medical examinations including pulmonary auscultation and pulmonary posterior-anterior X-ray. Pulmonary function tests were used for evaluation of pulmonary function. FVC, FEV , FEV %, FEV /FVC and saturation values were recorded.
Mean age was 67.1 ± 8.8 (44-82) years in the pseudoexfoliation group and 63.8 ± 9.4 (43-82) years in the control group (P > .05). Mean FEV was 1.60 ± 0.62 in the pseudoexfoliation group and 1.84 ± 0.61 in the control group (P = .036). Mean FEV % was 70.65 ± 23.89 in the pseudoexfoliation group and 83.46 ± 17.83 in the control group (P = .002). Mean FEV /FVC ratios were 0.72 ± 0.15 in the pseudoexfoliation group and 0.77 ± 0.11 in the control group (P = .043). No statistically significant differences were found between the groups for FVC, saturation or cigarette use.
These results suggest that there is decline in some pulmonary functions in pseudoexfoliation syndrome.
众所周知，假性剥脱物质会损害虹膜扩张功能。在肺组织中也发现了这种物质。本研究的目的是评估假性剥脱患者的肺功能。
这项前瞻性研究纳入了60例无任何肺部疾病的假性剥脱综合征患者和52例年龄及性别匹配的无任何肺部疾病的对照者。询问患者的吸烟情况以及是否存在任何全身性疾病，如糖尿病、动脉高血压和哮喘。所有病例均接受了全面的眼科和普通医学检查，包括肺部听诊和胸部后前位X线检查。采用肺功能测试来评估肺功能。记录用力肺活量（FVC）、第1秒用力呼气容积（FEV₁）、FEV₁%、FEV₁/FVC以及血氧饱和度值。
假性剥脱组的平均年龄为67.1±8.8（44 - 82）岁，对照组为63.8±9.4（43 - 82）岁（P＞0.05）。假性剥脱组的平均FEV₁为1.60±0.62，对照组为1.84±0.61（P = 0.036）。假性剥脱组的平均FEV₁%为70.65±23.89，对照组为83.46±17.83（P = 0.002）。假性剥脱组的平均FEV₁/FVC比值为0.72±0.15，对照组为0.77±0.11（P = 0.043）。两组在FVC、血氧饱和度或吸烟情况方面未发现统计学上的显著差异。
这些结果表明，假性剥脱综合征患者的某些肺功能有所下降。
