Montoro Casandra I, Duschek Stefan, Reyes Del Paso Gustavo A
Department of Psychology, University of Jaén, Spain.
UMIT - University for Health Sciences Medical Informatics and Technology, Hall in Tirol, Austria.
Biol Psychol. 2018 May;135:149-158. doi: 10.1016/j.biopsycho.2018.04.005. Epub 2018 Apr 13.
This study analyzed variability in cerebral blood flow velocity (CBFV) and possible underlying physiological mechanisms during rest and a mental arithmetic task. Blood flow velocities were bilaterally recorded by transcranial Doppler sonography in the anterior and middle cerebral arteries of 43 participants. Electrocardiography, continuous blood pressure (BP) and respiratory recordings were additionally obtained. Fast Fourier transformation revealed a spectral profile with two main components in CBFV, one in the very low frequency (VLF, 0.01-0.025 Hz), and the other in the low frequency band (LF, 0.075-0.11 Hz). During the task, CBFV variability decreased. While heart rate variability and respiration had only weak impacts, BP variability was closely associated with CBFV variability. LF CBFV variability correlated negatively with task performance. The findings indicate a connection between peripheral and cerebral hemodynamics, presumably mediated by the passive pressure-flow relationship and neural mechanisms. LF CBFV variability may constitute a suitable marker of mental effort load.
本研究分析了静息状态和心算任务期间脑血流速度（CBFV）的变异性以及可能的潜在生理机制。通过经颅多普勒超声对43名参与者大脑前动脉和中动脉的血流速度进行双侧记录。另外还记录了心电图、连续血压（BP）和呼吸情况。快速傅里叶变换显示CBFV频谱图有两个主要成分，一个在极低频（VLF，0.01 - 0.025Hz），另一个在低频带（LF，0.075 - 0.11Hz）。在任务期间，CBFV变异性降低。虽然心率变异性和呼吸的影响较弱，但血压变异性与CBFV变异性密切相关。低频CBFV变异性与任务表现呈负相关。研究结果表明外周和脑血流动力学之间存在联系，可能是由被动压力 - 流量关系和神经机制介导的。低频CBFV变异性可能是脑力负荷的一个合适指标。
