Kubota Toshiro
Comprehensive Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
Reprod Med Biol. 2007 Aug 6;6(3):157-164. doi: 10.1111/j.1447-0578.2007.00179.x. eCollection 2007 Sep.
In this review, it is proposed that the vasoactive agents endothelin (ET), nitric oxide (NO)/NO synthase (NOS) and carbon monoxide(CO)/heme oxygenase(HO) act directly on human endometrial functions and on ovarian functions in the normal menstrual cycle and in implantation periods. These vasoactive substances are likely to be important autocrine/paracrine factors that regulate a variety of physiological and pathological processes. The main actions of these agents are differentiation and implantation in the endometrial functions, and follicular growth, luteinization and atresia in the ovarian functions, in the tight connection between endometrial and ovarian systems during normal menstrual periods and during implantation (Reprod Med Biol 2007; : 157-164).
在本综述中，有人提出血管活性因子内皮素（ET）、一氧化氮（NO）/一氧化氮合酶（NOS）和一氧化碳（CO）/血红素氧合酶（HO）在正常月经周期和着床期直接作用于人类子宫内膜功能和卵巢功能。这些血管活性物质可能是调节多种生理和病理过程的重要自分泌/旁分泌因子。在正常月经期和着床期间，子宫内膜和卵巢系统紧密相连，这些因子的主要作用是在子宫内膜功能方面促进分化和着床，在卵巢功能方面促进卵泡生长、黄体化和闭锁（《生殖医学与生物学》2007年；：157 - 164）。
