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随机对照试验在结直肠手术后强化康复中扩展围手术期咨询。

Randomized Controlled Trial of Extended Perioperative Counseling in Enhanced Recovery After Colorectal Surgery.

机构信息

Department of Gastrointestinal and Emergency Surgery, Haukeland University Hospital, Bergen, Norway.

Department of Clinical Medicine, University of Bergen, Norway.

出版信息

Dis Colon Rectum. 2018 Jun;61(6):724-732. doi: 10.1097/DCR.0000000000001007.

Abstract

BACKGROUND

Enhanced recovery after surgery programs reduce the length of hospital stay in patients who undergo elective colorectal resection, but the reasons for this reduction are not well understood.

OBJECTIVE

The aim of this randomized controlled trial was to assess the impact of extended perioperative counseling in treatment groups that were otherwise the same with respect to enhanced recovery after surgery criteria.

DESIGN

Patients eligible for open or laparoscopic colorectal resection were randomly assigned to extended counseling (repeated information and guidance by a dedicated nurse) or standard counseling.

SETTINGS

This study was conducted at a single institution.

PATIENTS

Patients (n = 164) were randomly assigned to enhanced recovery after surgery plus extended counseling (n = 80) or enhanced recovery after surgery with standard counseling (n = 84).

MAIN OUTCOME MEASURES

The primary end point was the total length of hospital stay. Discharge criteria were defined. Secondary end points were postoperative complications, postoperative length of hospital stay, readmission rate, and mortality.

RESULTS

Total hospital stay was significantly shorter among patients randomly assigned to enhanced recovery after surgery plus extended counseling (median 5 (range 2-29) days vs 7 (range 2-39) days, p < 0.001). The 2 treatment groups differed in adherence to the elements of postoperative enhanced recovery after surgery such as mobilization and total oral intake. The 2 treatment groups did not differ in overall, major, and minor morbidity; reoperation rate; readmission rate; and 30-day mortality.

LIMITATIONS

The main limitation of this study was the absence of blinding.

CONCLUSIONS

Perioperative information and guidance were important factors in enhanced recovery after surgery care and were associated with a significantly shorter length of hospital stay. Our findings suggest that perioperative counseling enables patients to comply with the elements of postoperative enhanced recovery after surgery and thereby reduces the length of hospital stay. This study was registered with ClinicalTrials.gov (NCT01610726). See Video Abstract at http://links.lww.com/DCR/A505.

摘要

背景

手术康复计划可减少择期结直肠切除术患者的住院时间,但这种减少的原因尚不清楚。

目的

本随机对照试验旨在评估在接受手术康复计划的治疗组中,扩展围手术期咨询对治疗的影响,这些治疗组在手术康复计划标准方面是相同的。

设计

符合开腹或腹腔镜结直肠切除术条件的患者被随机分配到扩展咨询(由专门护士进行重复信息和指导)或标准咨询。

地点

本研究在一家机构进行。

患者

符合条件的患者(n=164)被随机分配到手术康复计划加扩展咨询(n=80)或手术康复计划加标准咨询(n=84)。

主要观察指标

主要终点是总住院时间。定义了出院标准。次要终点是术后并发症、术后住院时间、再入院率和死亡率。

结果

随机分配到手术康复计划加扩展咨询的患者总住院时间明显缩短(中位数 5(范围 2-29)天与 7(范围 2-39)天,p<0.001)。2 种治疗组在术后康复计划的各个元素(如活动和总口服摄入)的依从性上存在差异。2 种治疗组在总发病率、主要发病率和次要发病率、再次手术率、再入院率和 30 天死亡率方面无差异。

局限性

本研究的主要局限性是缺乏盲法。

结论

围手术期信息和指导是手术康复护理的重要因素,与显著缩短住院时间有关。我们的研究结果表明,围手术期咨询使患者能够遵守术后康复计划的各个元素,从而缩短住院时间。本研究在 ClinicalTrials.gov 注册(NCT01610726)。见视频摘要,网址:http://links.lww.com/DCR/A505。

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