Akdag Mehmet, Dasdag Suleyman, Canturk Fazile, Akdag Mehmet Zulkuf
a Department of Otolaryngology-Head and Neck Surgery , Medical School of Dicle University , Diyarbakir , Turkey.
b Department of Biophysics , Medical School of Istanbul Medeniyet University , Istanbul , Turkey.
Electromagn Biol Med. 2018;37(2):66-75. doi: 10.1080/15368378.2018.1463246. Epub 2018 Apr 18.
The aim of this study was to investigate effect of radiofrequency radiation (RFR) emitted from mobile phones on DNA damage in follicle cells of hair in the ear canal. The study was carried out on 56 men (age range: 30-60 years old)in four treatment groups with n = 14 in each group. The groups were defined as follows: people who did not use a mobile phone (Control), people use mobile phones for 0-30 min/day (second group), people use mobile phones for 30-60 min/day (third group) and people use mobile phones for more than 60 min/day (fourth group). Ear canal hair follicle cells taken from the subjects were analyzed by the Comet Assay to determine DNA damages. The Comet Assay parameters measured were head length, tail length, comet length, percentage of head DNA, tail DNA percentage, tail moment, and Olive tail moment. Results of the study showed that DNA damage indicators were higher in the RFR exposure groups than in the control subjects. In addition, DNA damage increased with the daily duration of exposure. In conclusion, RFR emitted from mobile phones has a potential to produce DNA damage in follicle cells of hair in the ear canal. Therefore, mobile phone users have to pay more attention when using wireless phones.
本研究的目的是调查手机发出的射频辐射（RFR）对耳道毛发毛囊细胞中DNA损伤的影响。该研究对56名男性（年龄范围：30至60岁）进行，分为四个治疗组，每组n = 14。分组如下：不使用手机的人（对照组）、每天使用手机0至30分钟的人（第二组）、每天使用手机30至60分钟的人（第三组）和每天使用手机超过60分钟的人（第四组）。通过彗星试验分析从受试者采集的耳道毛囊细胞，以确定DNA损伤情况。测量的彗星试验参数有头部长度、尾部长度、彗星长度、头部DNA百分比、尾部DNA百分比、尾部矩和橄榄尾矩。研究结果表明，RFR暴露组的DNA损伤指标高于对照组受试者。此外，DNA损伤随每日暴露时间的增加而增加。总之，手机发出的RFR有可能在耳道毛发毛囊细胞中产生DNA损伤。因此，手机用户在使用无线电话时必须更加注意。
