Division of Hematology, Children's National Health System, Washington, District of Columbia.
Shady Grove Fertility, Rockville, Maryland.
Pediatr Blood Cancer. 2018 Aug;65(8):e27102. doi: 10.1002/pbc.27102. Epub 2018 Apr 18.
Pre-implantation genetic diagnosis (PGD) is an option for parents who have a child with sickle cell disease (SCD) to have another child without SCD. We conducted a survey of 19 parents with at least one child with SCD to investigate views on PGD. Before education, 44% of parents were aware of PGD. All parents rated PGD education as important. All parents considering another child also reported interest in using PGD if insurance covered its costs. Parents who have a child with SCD appear to be interested in PGD and educational tools informing this group about PGD should be developed.
胚胎植入前遗传学诊断 (PGD) 是一种可供患有镰状细胞病 (SCD) 的儿童的父母选择的方法，他们可以生育没有 SCD 的孩子。我们对 19 名至少有一名 SCD 患儿的父母进行了一项调查，以了解他们对 PGD 的看法。在接受教育之前，有 44%的父母了解 PGD。所有父母都认为 PGD 教育很重要。所有考虑再要一个孩子的父母，如果保险能覆盖 PGD 的费用，他们也表示有兴趣使用 PGD。患有 SCD 的儿童的父母似乎对 PGD 感兴趣，应该为该群体开发教育工具，让他们了解 PGD。
