Lamtha Sangey Chhophel, Tripathi Manish Kumar, Bhutia Karma Doma, Karthak Caroline
Trop Gastroenterol. 2016 Jan-Mar;37(1):42-5. doi: 10.7869/tg.318.
The etiology of gastric cancer is multifactorial. Marked differences in the incidence of gastric cancer among different ethnic groups living in the same geographical area have been observed.
This study looked at ethnic and dietary factors in patients with gastric cancer diagnosed at a tertiary referral centre in Sikkim over a period of one year. Patients of 60 years and above were included in the study and divided into four ethnic groups : Bhutias, Lepchas, Rais and other groups.
211 cases underwent upper GI endoscopy and 32 were diagnosed to have gastric cancer. Gastric cancer incidence was highest in Bhutia ethnic group. A trend towards higher intake of smoked meats, fermented vegetables, salt tea, and H.pylori positivity in the Bhutia ethnic group was associated with higher incidence of gastric cancer as compared to other ethnic groups.
The study with a referral centre bias showed that Bhutia ethnic group had a higher incidence of gastric cancer as compared to other ethnic groups.
胃癌的病因是多因素的。在同一地理区域生活的不同种族群体中，胃癌发病率存在显著差异。
本研究观察了在锡金一家三级转诊中心一年内确诊的胃癌患者的种族和饮食因素。60岁及以上的患者纳入研究，并分为四个种族群体：不丹族、雷布查族、拉伊族和其他群体。
211例患者接受了上消化道内镜检查，32例被诊断为胃癌。不丹族胃癌发病率最高。与其他种族群体相比，不丹族食用烟熏肉、发酵蔬菜、咸茶的摄入量较高且幽门螺杆菌阳性率较高的趋势与胃癌发病率较高有关。
这项存在转诊中心偏倚的研究表明，与其他种族群体相比，不丹族胃癌发病率较高。
