Sherwin B B
Department of Psychology, McGill University, Montreal, Quebec, Canada.
J Affect Disord. 1988 Mar-Apr;14(2):177-87. doi: 10.1016/0165-0327(88)90061-4.
Otherwise healthy surgically menopausal women who had been receiving either an intramuscular estrogen-androgen (E-A) combined preparation or estrogen alone (E) long-term had more positive moods than an untreated control group (CON) coincident with their higher levels of circulating estradiol (E2). Women who received both E2 and testosterone (T) felt more composed, elated, and energetic than those who were given E alone. These findings confirm that mood covaries with circulating estradiol levels in generally healthy, nondepressed women. Possible mechanisms of action of the sex steroids on affect are discussed.
在其他方面健康的手术绝经女性，长期接受肌肉注射雌激素 - 雄激素（E - A）联合制剂或单独使用雌激素（E），与未治疗的对照组（CON）相比，她们的情绪更积极，同时其循环雌二醇（E2）水平更高。接受E2和睾酮（T）的女性比仅接受E的女性感觉更镇定、愉悦和精力充沛。这些发现证实，在总体健康、无抑郁的女性中，情绪与循环雌二醇水平相关。文中讨论了性类固醇对情感影响的可能作用机制。
