Mankon Sub-divisional Hospital, Bamenda, Northwest Region, Cameroon.
Ibal Sub-Divisional Hospital, Oku, Northwest Region, Cameroon.
J Trop Pediatr. 2019 Feb 1;65(1):90-97. doi: 10.1093/tropej/fmy017.
We assessed the accuracy of the Nelson, Best Guess and Advanced Pediatric Life Support (APLS) formulae in estimating weight in a suburban Cameroonian pediatric population, by conducting a cross-sectional study using 544 children aged 1 month to 12 years. Agreement between measured and estimated weight was poor for Nelson [concordance correlation coefficient (CCC) 0.89 (95% confidence interval (CI) 0.87-0.90)] and Best Guess [CCC 0.88 (95% CI 0.86-0.90)] formulae, and moderate for the APLS formula [CCC 0.92 (95% CI 0.90-0.93)]. On Bland-Altman analysis, all three methods had limits of agreement (APLS -42.2 to -45.6%, Best Guess -42.7 to -55.1%, Nelson -36.4 to -42.4%) above the -10 to -10% set as criteria for clinical agreement. Conclusively, the accuracy of all three formulae was clinically unacceptable in our study population, suggesting the need for studies aimed at deriving more accurate formulae adapted for use in our context.
我们通过对喀麦隆一个郊区的 544 名 1 个月至 12 岁的儿童进行横断面研究，评估了 Nelson、Best Guess 和高级儿科生命支持（APLS）公式在估计体重方面的准确性。Nelson [一致性相关系数（CCC）0.89（95%置信区间（CI）0.87-0.90）]和 Best Guess [CCC 0.88（95% CI 0.86-0.90）]公式在测量体重和估计体重之间的一致性较差，APLS 公式的一致性为中等[CCC 0.92（95% CI 0.90-0.93）]。在 Bland-Altman 分析中，所有三种方法的一致性界限（APLS -42.2 至-45.6%，Best Guess -42.7 至-55.1%，Nelson -36.4 至-42.4%）均高于 -10%至-10%的临床一致性标准。总之，在我们的研究人群中，所有三种公式的准确性在临床上都不能接受，这表明需要研究旨在为我们的背景下开发更准确的公式。
