Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, 53115 Bonn, Germany; Molecular Immunology in Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.
Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany; Department of MedicineI, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, 24105 Kiel, Germany.
Immunity. 2018 Apr 17;48(4):608-613. doi: 10.1016/j.immuni.2018.03.022.
Chronic inflammatory diseases represent an increasing medical burden, yet neither tools to predict the individual disease course nor causal cures are at hand. We discuss opportunities for systems medicine to derive precise, individualized disease models and outline the European consortium SYSCID as part of the roadmap to clinical practice.
慢性炎症性疾病是一个日益沉重的医学负担，但目前既没有预测个体疾病进程的工具，也没有根治疾病的方法。我们讨论了系统医学在获得精确的个体化疾病模型方面的机会，并概述了作为临床实践路线图一部分的欧洲 SYSCID 联合会。
