Liu Wu, Gao Meng, Liang Xida
Ophthalmologica. 2018;240(1):1-7. doi: 10.1159/000488118. Epub 2018 Apr 18.
Perfluorocarbon liquid (PFCL) has been widely used in vitreoretinal surgeries, especially in retinal detachment treatment. A prominent complication of intraoperative PFCL application is inadvertent subretinal PFCL retention. Subfoveal PFCL, even in small amounts, receives much attention due to its potential side effect on the macular structure and function. Whether to observe with follow-up or to deal with surgery is often an intractable problem in the management of subfoveal PFCL. Safety and necessity are the 2 key issues in considering surgical treatment, that is, can we avoid surgically induced macular injury and will surgery be beneficial for the recovery of vision? Herein, the authors review sub-foveal PFCL retention with its risk factors, morphological manifestations, pathological studies, clinical natural consequences, and different surgical methods with their outcomes. Analysis of the existing literature shows that visual acuity improved significantly after subfoveal PFCL removal or displacement and was positively correlated with visual acuity before the operation.
全氟碳化合物液体（PFCL）已广泛应用于玻璃体视网膜手术，尤其是在视网膜脱离治疗中。术中应用PFCL的一个突出并发症是意外的视网膜下PFCL残留。即使是少量的黄斑下PFCL，因其对黄斑结构和功能的潜在副作用而备受关注。在黄斑下PFCL的处理中，是进行随访观察还是进行手术治疗往往是一个棘手的问题。安全性和必要性是考虑手术治疗的两个关键问题，即我们能否避免手术引起的黄斑损伤以及手术是否有利于视力恢复？在此，作者综述了黄斑下PFCL残留及其危险因素、形态学表现、病理学研究、临床自然转归以及不同手术方法及其结果。对现有文献的分析表明，黄斑下PFCL清除或移位后视力显著改善，且与术前视力呈正相关。
