Department of Radiology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Korea.
Division of Biomedical Engineering, Hankuk University of Foreign Studies, Oedae-ro 81, Mohyeon-myeon, Cheoin-gu, Yongin-si, Gyeonggi-do, Korea.
Sci Rep. 2018 Apr 18;8(1):6197. doi: 10.1038/s41598-018-24377-0.
We investigated addition of strain and shear wave elastography to conventional ultrasonography for the qualitative and quantitative assessment of breast masses; cut-off points were determined for strain ratio, elasticity ratio, and visual score for differentiating between benign and malignant masses. In all, 108 masses from 94 patients were evaluated with strain and shear wave elastography and scored for suspicion of malignancy, visual score, strain ratio, and elasticity ratio. The diagnostic performance between ultrasonography alone and ultrasonography combined with either type of elastography was compared; cut-off points were determined for strain ratio, elasticity ratio, and visual score. Of the 108 masses, 44 were malignant and 64 were benign. The areas under the curves were significantly higher for strain and shear wave elastography-supplemented ultrasonography (0.839 and 0.826, respectively; P = 0.656) than for ultrasonography alone (0.764; P = 0.018 and 0.035, respectively). The diagnostic performances of strain and elasticity ratios were similar when differentiating benign from malignant masses. Cut-off values for strain ratio, elasticity ratio, and visual scores for strain and shear wave elastography were 2.93, 4, 3, and 2, respectively. Both forms of elastography similarly improved the diagnostic performance of conventional ultrasonography in the qualitative and quantitative assessment of breast masses.
我们研究了应变和剪切波弹性成像在常规超声中的应用，以定性和定量评估乳腺肿块；确定了应变比、弹性比和视觉评分的截断值，用于区分良性和恶性肿块。共有 94 例患者的 108 个肿块接受了应变和剪切波弹性成像评估，并对恶性可疑程度进行了评分、视觉评分、应变比和弹性比评分。比较了单独使用超声与联合使用任何一种弹性成像的诊断性能；确定了应变比、弹性比和视觉评分的截断值。在 108 个肿块中，44 个为恶性，64 个为良性。应变和剪切波弹性成像补充超声的曲线下面积明显高于单独超声（分别为 0.839 和 0.826；P=0.656）。应变和弹性比在区分良性和恶性肿块方面的诊断性能相似。应变比、弹性比和应变和剪切波弹性成像的视觉评分的截断值分别为 2.93、4、3 和 2。两种形式的弹性成像均能改善常规超声在定性和定量评估乳腺肿块方面的诊断性能。
