Yoon Jung Hyun, Song Mi Kyung, Kim Eun-Kyung
Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Department of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
Ultrasound Med Biol. 2016 Aug;42(8):1800-6. doi: 10.1016/j.ultrasmedbio.2016.03.030. Epub 2016 May 7.
The purpose of this study was to evaluate the diagnostic performances of semi-quantitative strain ratio measured by using one region-of-interest (ROI) on breast US elastography images. Two hundred one breast masses of 165 women (mean age: 47.2 y) were included. Ultrasonography (US) and elastography images of the masses were obtained and prospectively analyzed according to elasticity pattern, strain ratio, and final Breast Imaging-Reporting and Data System (BI-RADS) assessments. Of the 201 breast masses, 127 (63.2%) were benign and 74 (36.8%) were malignant. Elastography pattern and strain ratio (cut-off of 1.44) had significantly higher specificity than gray-scale US, 39.4% and 61.4% versus 29.1%, respectively (all p < 0.05). Area under the receiver operating characteristics curve (Az) was highest for gray-scale US (0.646), without statistical significances, than for elastography pattern (0.596, p = 0.159) or strain ratio (0.625, p = 0.610). Semi-quantitative strain ratio measured from one ROI has comparable diagnostic performances to gray-scale US, which may contribute to more accurate differential diagnosis of breast masses seen on US.
本研究的目的是评估在乳腺超声弹性成像图像上使用一个感兴趣区域（ROI）测量的半定量应变率的诊断性能。纳入了165名女性的201个乳腺肿块（平均年龄：47.2岁）。获取了肿块的超声（US）和弹性成像图像，并根据弹性模式、应变率和最终的乳腺影像报告和数据系统（BI-RADS）评估进行前瞻性分析。在201个乳腺肿块中，127个（63.2%）为良性，74个（36.8%）为恶性。弹性成像模式和应变率（临界值为1.44）的特异性显著高于灰阶超声，分别为39.4%和61.4%，而灰阶超声为29.1%（所有p<0.05）。灰阶超声的受试者操作特征曲线下面积（Az）最高（0.646），与弹性成像模式（0.596，p = 0.159）或应变率（0.625，p = 0.610）相比，无统计学意义。从一个ROI测量的半定量应变率具有与灰阶超声相当的诊断性能，这可能有助于更准确地鉴别超声所见乳腺肿块。
