Pazmiño P
Nephrology and Hypertension Center, Texas Tech University Health Science Center School of Medicine, El Paso.
Am J Nephrol. 1988;8(1):68-70. doi: 10.1159/000167557.
A case of acute renal failure associated with aztreonam therapy is reported. A man, age 70, with infections due to Klebsiella pneumoniae and Enterobacter cloaca was treated for 9 days with aztreonam and presented with a generalized maculopapular rash, fever, eosinophilia, worsening renal function and increased IgE levels and eosinophiluria. Aztreonam was then discontinued and the patient was treated with supportive measures and steroids and his renal failure reversed over the course of 5 days. This appears to be one of the first cases of acute renal failure associated with aztreonam.
报告了1例与氨曲南治疗相关的急性肾衰竭病例。一名70岁男性，因肺炎克雷伯菌和阴沟肠杆菌感染，接受氨曲南治疗9天，出现全身性斑丘疹、发热、嗜酸性粒细胞增多、肾功能恶化、免疫球蛋白E水平升高及嗜酸性粒细胞尿。随后停用氨曲南，患者接受支持治疗和类固醇治疗，其肾衰竭在5天内逆转。这似乎是首例与氨曲南相关的急性肾衰竭病例之一。
