中国美沙酮维持治疗项目中的教育与行为咨询：一项随机对照试验
Educational and Behavioral Counseling in a Methadone Maintenance Treatment Program in China: A Randomized Controlled Trial.
作者信息
Liu Pulin, Song Ranran, Zhang Yao, Liu Cheng, Cai Bingxi, Liu Xuebing, Li Jiaoyuan, Chen Xueqin, Ke Juntao, Lou Jiao, Chen Wei, Zhu Beibei, Zou Li, Yang Yang, Zhu Ying, Gong Yajie, Zhong Rong, Miao Xiaoping
机构信息
Department of Epidemiology and Biostatistics, Ministry of Education and Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubation), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wuhan Centers for Disease Prevention and Control, Wuhan, China.
出版信息
Front Psychiatry. 2018 Apr 4;9:113. doi: 10.3389/fpsyt.2018.00113. eCollection 2018.
INTRODUCTION
Methadone maintenance treatment (MMT) programs have been rapidly scaled up nationwide in China in recent years, and psychosocial intervention measures, including counseling, were recommended for improving the outcomes of MMT. However, the effectiveness of counseling in MMT programs remains controversial. This study investigated the efficacy of educational and behavioral counseling (EBC) mode in an MMT program in China.
METHODS
A total of 125 eligible participants were randomized to EBC or a control group. Patients in the EBC group received weekly, manual-guided, group educational counseling for 8 weeks and individual behavioral counseling for the next 8 weeks. Patients in the control group received standard methadone maintenance treatment as usual (TAU).
RESULTS
During the 16-week trial, the EBC group showed better treatment attendance ( = 0.022) and a greater increase in knowledge regarding heroin addiction ( = 0.001) and MMT ( = 0.005) than did the TAU group. Between the two groups, there were no significant differences regarding drug abstinence and reduction of risky behaviors.
CONCLUSION
EBC affiliated with MMT improved patients' cognition and adherence to treatment, facilitating their successful recovery.
CLINICAL TRIAL REGISTRATION
ChiCTR-IOR-15006673: http://www.chictr.org.cn.
引言
近年来，美沙酮维持治疗（MMT）项目在中国全国范围内迅速扩大规模，并且推荐采用包括咨询在内的心理社会干预措施来改善MMT的治疗效果。然而，咨询在MMT项目中的有效性仍存在争议。本研究调查了教育与行为咨询（EBC）模式在中国一个MMT项目中的疗效。
方法
总共125名符合条件的参与者被随机分为EBC组或对照组。EBC组的患者接受为期8周的每周一次、手册指导的团体教育咨询，随后8周接受个体行为咨询。对照组的患者接受常规标准美沙酮维持治疗（TAU）。
结果
在为期16周的试验期间，EBC组的治疗出勤率更高（=0.022），并且在海洛因成瘾知识（=0.001）和美沙酮维持治疗知识（=0.005）方面的增长幅度大于TAU组。两组之间在戒毒和减少危险行为方面没有显著差异。
结论
与MMT相关的EBC改善了患者的认知和治疗依从性，促进了他们的成功康复。
临床试验注册
ChiCTR-IOR-15006673：http://www.chictr.org.cn 。
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