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[广泛双侧肺切除术后心肌的形态功能变化]

[Morphofunctional changes in the myocardium after extensive bilateral resection of the lungs].

作者信息

Vaĭda R I, Gerasimiuk I E

出版信息

Arkh Anat Gistol Embriol. 1988 Feb;94(2):29-35.

PMID:2967071
Abstract

In the experiment, performed on 89 dogs, after 67-75% resection of the lungs, functional morphology of the myocardium has been studied by means of histological, electron microscopical and morphometrical methods. Bilateral extensive resections of the lungs are accompanied with hypertrophy of the cardiac muscle, that is revealed at all the levels of its structural organization. Simultaneously, the hypertrophy develops against the background of dystrophic and destructive changes of the myocardium, their depth and extensiveness correlate with duration of the postoperative observations. If an extrapulmonary anastomosis is formed between the inferior lobular pulmonary artery and the corresponding vein before the resection of 67-75% of the lungs, it eliminates the acute overloading of the right ventricle, makes better conditions for development of compensatory-adaptive processes in the myocardium, prevents advancement of the cardio-pulmonary deficiency during the postoperative period.

摘要

在对89只狗进行的实验中,在切除67 - 75%的肺组织后,通过组织学、电子显微镜和形态计量学方法研究了心肌的功能形态。双侧广泛切除肺组织会伴有心肌肥大,这在心肌结构组织的各个层面都有体现。同时,肥大是在心肌营养不良和破坏性改变的背景下发生的,其深度和范围与术后观察的持续时间相关。如果在切除67 - 75%的肺组织之前,在下叶肺动脉和相应静脉之间形成肺外吻合,可消除右心室的急性过载,为心肌代偿 - 适应过程的发展创造更好的条件,防止术后心肺功能不全的进展。

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