胎儿及新生儿播散性横纹肌样瘤的超声表现

Ultrasound Presentation of a Disseminated Fetal and Neonatal Rhabdoid Tumor.

作者信息

Joueidi Yolaine, Rousselin Aline, Rozel Céline, Loget Philippe, Ranchere Vince Dominique, Odent Sylvie, Bourdeaut Franck, Lavoue Vincent, Le Lous Maela

机构信息

Department of Obstetrics and Gynaecology, CHU de Rennes, Hospital Anne de Bretagne, 16 Bd de Bulgarie, BP 90347, 35 203 Rennes Cedex 2, France.

Department of Radiology, CHU de Rennes, Hospital Anne de Bretagne, 16 Bd de Bulgarie, BP 90347, 35 203 Rennes Cedex 2, France.

出版信息

Case Rep Obstet Gynecol. 2018 Jan 31;2018:6073204. doi: 10.1155/2018/6073204. eCollection 2018.

DOI:10.1155/2018/6073204

PMID:29670784

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5833875/

Abstract

This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. Fetal ultrasound showed signs of a disseminated tumor affecting the left armpit, liver, spleen, and limbs. A caesarian section was performed because of signs of fetal distress. Immunohistochemical analysis of a fetal biopsy showed deletion of the gene. Pathological analysis of the placenta showed a rhabdoid tumor invading both fetal and maternal compartments. The mother underwent a whole-body MRI, and no metastasis was found. To the best of our knowledge, this is the first report of a disseminated rhabdoid tumor invading both fetal and maternal compartments.

摘要

这是一例关于一名29岁接受免疫抑制治疗的女性在妊娠32周时发现的播散性胎儿横纹肌样瘤的病例报告。母亲因胎动减少前来咨询。胎儿超声显示有播散性肿瘤的迹象，累及左腋窝、肝脏、脾脏和四肢。由于胎儿窘迫迹象，进行了剖宫产。对胎儿活检进行的免疫组化分析显示该基因缺失。胎盘的病理分析显示横纹肌样瘤侵犯了胎儿和母体部分。母亲接受了全身MRI检查，未发现转移。据我们所知，这是首例播散性横纹肌样瘤侵犯胎儿和母体部分的报告。