变形链球菌英布里特株葡糖基转移酶A基因（gtfA）的序列分析
Sequence analysis of the glucosyltransferase A gene (gtfA) from Streptococcus mutans Ingbritt.
作者信息
Ferretti J J, Huang T T, Russell R R
机构信息
Department of Microbiology and Immunology, University of Oklahoma Health Science Center, Oklahoma City 73190.
出版信息
Infect Immun. 1988 Jun;56(6):1585-8. doi: 10.1128/iai.56.6.1585-1588.1988.
Abstract
The complete nucleotide sequence of a 2.4-kilobase fragment containing the glucosyltransferase A gene (gtfA) of Streptococcus mutans Ingbritt (serotype c) was determined. The gtfA gene contains 481 codons and specifies a protein of molecular weight 55,665. There is no evidence of a signal peptide in the protein or that the glucosyltransferase A enzyme is secreted. No sequence homologies were observed between the gtfA gene or protein and the gtfI or gtfB gene and its protein.
摘要
测定了变形链球菌英布里特株（血清型c）中包含葡糖基转移酶A基因（gtfA）的一个2.4千碱基片段的完整核苷酸序列。gtfA基因含有481个密码子，编码一种分子量为55,665的蛋白质。在该蛋白质中没有信号肽的证据，也没有证据表明葡糖基转移酶A酶是分泌型的。在gtfA基因或蛋白质与gtfI或gtfB基因及其蛋白质之间未观察到序列同源性。
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