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超声引导下手动真空抽吸治疗早期妊娠流产的疗效、可行性及患者可接受性。

Efficacy, feasibility and patient acceptability of ultrasound-guided manual vacuum aspiration for treating early pregnancy loss.

作者信息

Chung Jacqueline Pui Wah, Chung Cathy Hoi Sze, Mak Jennifer Sze Man, Li Tin Chiu, Kong Grace Wing Shan

机构信息

Department of Obstetrics and Gynaecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.

出版信息

Aust N Z J Obstet Gynaecol. 2019 Feb;59(1):71-76. doi: 10.1111/ajo.12811. Epub 2018 Apr 19.

DOI:10.1111/ajo.12811
PMID:29672838
Abstract

BACKGROUND

Ultrasound-guided manual vacuum aspiration (USG-MVA) is an effective but underutilised alternative to medical or surgical evacuation of the uterus following first trimester miscarriage.

AIMS

To evaluate the efficacy, feasibility and patient acceptability of USG-MVA for treating early pregnancy loss.

MATERIAL AND METHODS

We invited patients with early pregnancy losses to participate in this prospective cohort study. We reviewed the medical records of the participants and their visual analogue pain score during MVA. Primary outcomes were efficacy, feasibility and patient acceptability of USG-MVA. Secondary outcomes included the success rate of culture of chorionic villi for chromosomal analysis and complications from the USG-MVA procedure.

RESULTS

We included a consecutive series of 35 women who underwent the USG-MVA procedure. The efficacy of USG-MVA in achieving complete evacuation was 97.1%. The procedure was well tolerated and the mean procedure-related pain score was 6.25 out of 10 (SD 1.55). Overall, all patients were satisfied with the procedure. The successful culture rate of chromosomal analysis was 94.3%. There were no major complications.

CONCLUSION

USG-MVA is an effective treatment for the management of early pregnancy loss in an out-patient setting. It is an alternative to surgical evacuation under general anaesthesia, particularly for women desiring chromosomal analysis of products of conception. Further studies are required to investigate its health-related and economic benefits in hospital service provision.

摘要

背景

超声引导下手动真空吸引术(USG-MVA)是孕早期流产后子宫医学或手术排空的一种有效但未得到充分利用的替代方法。

目的

评估USG-MVA治疗早期妊娠丢失的有效性、可行性和患者可接受性。

材料与方法

我们邀请早期妊娠丢失的患者参与这项前瞻性队列研究。我们回顾了参与者的病历及其在MVA期间的视觉模拟疼痛评分。主要结局是USG-MVA的有效性、可行性和患者可接受性。次要结局包括用于染色体分析的绒毛膜绒毛培养成功率和USG-MVA手术的并发症。

结果

我们纳入了连续35例行USG-MVA手术的女性。USG-MVA实现完全排空的有效性为97.1%。该手术耐受性良好,与手术相关的平均疼痛评分为6.25分(满分10分,标准差1.55)。总体而言,所有患者对该手术都很满意。染色体分析的成功培养率为94.3%。没有重大并发症。

结论

USG-MVA是门诊治疗早期妊娠丢失的有效方法。它是全身麻醉下手术排空的一种替代方法,尤其适用于希望对妊娠产物进行染色体分析的女性。需要进一步研究以调查其在医院服务提供方面的健康相关和经济效益。

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