Organic Synthesis and Catalysis Lab, Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Knowledge City, Sector 81, S. A. S. Nagar, Manauli PO, Punjab, 140306, India.
Chem Asian J. 2018 Jul 4;13(13):1642-1653. doi: 10.1002/asia.201800389. Epub 2018 Jun 5.
Cyclopentanoids are omnipresent in natural products and pharmaceutically relevant compounds. Among them, cyclopenta-fused arenes and heteroarenes possess impressive biological properties and play significant role in materials science. Consequently, several notable methods have been developed for their synthesis over the years. In this review, we mainly described metal-free and organocatalytic approaches that led to the construction of pentannulated arenes and heteroarenes.
环戊烷类化合物在天然产物和药物相关化合物中普遍存在。其中,稠合的芳环和杂芳环具有令人印象深刻的生物性质,并在材料科学中发挥着重要作用。因此,多年来已经开发出几种用于合成它们的显著方法。在这篇综述中,我们主要描述了导致五氮芳环和杂芳环构建的无金属和有机催化方法。