使用超极化氙磁共振成像的脑成像
Brain Imaging Using Hyperpolarized Xe Magnetic Resonance Imaging.
作者信息
Chahal Simrun, Prete Braedan R J, Wade Alanna, Hane Francis T, Albert Mitchell S
机构信息
Lakehead University, Thunder Bay, ON, Canada.
Lakehead University, Thunder Bay, ON, Canada; Thunder Bay Regional Health Research Institute, Thunder Bay, ON, Canada.
出版信息
Methods Enzymol. 2018;603:305-320. doi: 10.1016/bs.mie.2018.01.027. Epub 2018 Mar 23.
Hyperpolarized (HP) Xe magnetic resonance imaging (MRI) is a novel iteration of traditional MRI that relies on detecting the spins of H. Since Xe is a gaseous signal source, it can be used for lung imaging. Additionally, Xe dissolves in the blood stream and can therefore be detectable in the brain parenchyma and vasculature. In this work, we provide detailed information on the protocols that we have developed to image Xe within the brains of both rodents and human subjects.
超极化（HP）氙磁共振成像（MRI）是传统MRI的一种新型迭代技术，它依赖于检测氢的自旋。由于氙是一种气态信号源，它可用于肺部成像。此外，氙可溶解于血流中，因此在脑实质和血管系统中也可被检测到。在本研究中，我们提供了关于我们所开发的用于对啮齿动物和人类受试者大脑中的氙进行成像的方案的详细信息。
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