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[溶剂在皮肤变化发展中的作用]

[The role of solvents in the development of skin changes].

作者信息

Kieć-Swierczyńska M

机构信息

Instytutu Medycyny Pracy im. prof. dra med. Jerzego Nofera w Lodzi.

出版信息

Med Pr. 1987;38(6):447-52.

PMID:2967417
Abstract

The dermatological tests covered 289 rubber industry workers occupationally exposed to organic solvents and rubber. The control group involved 95 subjects. All the subjects underwent epidermal tests with routine allergens, naephtha and 11 rubber allergens. Altogether, dermatoses have been diagnosed in 32.8% of persons exposed to solvents and rubber, 12.1% of subjects developed dermatitis of hands and forearms, whereas 2.8%--trophic lesions of nails. 6.2% were sensitized to rubber allergens, 13.5%--to chromium compounds, and 3.8%--to cobalt compounds. The number of cases of hand dermatitis and nail lesions was found to increase with age and length of employment. Similarly, the allergy prevalence increased with age and duration of exposure to solvents and rubber. In 40% of dermatitis-affected subjects, sensitization to rubber allergens was an aetiological factor, in 60%--hand dermatitis resulted from irritating effects of organic solvents.

摘要

对289名职业性接触有机溶剂和橡胶的橡胶行业工人进行了皮肤病学检测。对照组有95名受试者。所有受试者均接受了常规变应原、石脑油和11种橡胶变应原的表皮试验。总共,32.8%接触溶剂和橡胶的人被诊断患有皮肤病,12.1%的受试者出现手部和前臂皮炎,而2.8%出现指甲营养性病变。6.2%对橡胶变应原致敏,13.5%对铬化合物致敏,3.8%对钴化合物致敏。发现手部皮炎和指甲病变的病例数随年龄和工作年限增加而增多。同样,过敏患病率也随年龄以及接触溶剂和橡胶的时长增加而上升。在40%患皮炎的受试者中,对橡胶变应原致敏是一个病因,在60%的病例中,手部皮炎是由有机溶剂的刺激作用引起的。

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