Rodis J F, Vintzileos A M, Campbell W A, Nochimson D J
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington.
Obstet Gynecol. 1988 Jun;71(6 Pt 2):976-7.
We describe a case of spontaneous resolution of a cystic hygroma between 14-16 weeks' gestation in a fetus with trisomy 21 who, at termination at 19 weeks, revealed only mild webbing of the neck. Redundant nuchal skin folds are among the most common features of trisomy 21. Our case supports the hypothesis that this redundant skin of the fetal neck represents early cystic hygromas, which resolve in utero before 16 weeks' gestation.
我们描述了一例21三体胎儿在孕14至16周时囊状水瘤自然消退的病例，该胎儿在孕19周终止妊娠时，仅显示轻度颈部蹼状畸形。多余的颈部皮肤褶皱是21三体最常见的特征之一。我们的病例支持这样一种假说，即胎儿颈部的这种多余皮肤代表早期囊状水瘤，其在孕16周前在子宫内消退。
