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34年间单中心淋巴管瘤的自然消退情况

Spontaneous Regression of Lymphangiomas in a Single Center Over 34 Years.

作者信息

Kato Motoi, Watanabe Shoji, Kato Reiko, Kawashima Hiroshi, Iida Takuya, Watanabe Azusa

机构信息

Department of Plastic and Reconstructive Surgery, Lymph Clinic, Saitama Children's Medical Center, Saitma, Japan; Department of Pediatric Surgery, Saitama Children's Medical Center, Saitma, Japan; and Department of Plastic and Reconstructive Surgery, The University of Tokyo, Tokyo, Japan.

出版信息

Plast Reconstr Surg Glob Open. 2017 Sep 25;5(9):e1501. doi: 10.1097/GOX.0000000000001501. eCollection 2017 Sep.

DOI:10.1097/GOX.0000000000001501
PMID:29062665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5640371/
Abstract

BACKGROUND

A lymphangioma, also called a lymphatic malformation, is a congenital condition that frequently occurs in young children. It is classified into 3 groups depending on the size of the cysts (macrocystic, microcystic, and mixed). Spontaneous regression occurs in some cases; however, the characteristics of patients who show regression have not been studied previously. Furthermore, the types and the timing of the initial treatment are still controversial. Therefore, we statistically analyzed the occurrence of short-term spontaneous regression, patient age at original occurrence, cyst types, cyst sizes, and cyst locations in patients diagnosed with peripheral localized lymphangiomas in a single children center over 34 years.

METHODS

We retrospectively collected the data of 153 patients and reviewed the medical charts.

RESULTS

Spontaneous regression occurred only in macrocystic or mixed type; regression was most frequent in patients who, at the time of onset, were more than 2 years old.

CONCLUSIONS

We concluded that elderly patients with macrocystic or mixed type lymphangioma may have to wait for treatment for over 3 months from the initial onset. Conversely, microcystic type could not be expected to show regression in a short period, and prompt initiation of the treatments may be required. The difference of the regression or not may depend on the characteristics of the lymph flow.

摘要

背景

淋巴管瘤,也称为淋巴管畸形,是一种常见于幼儿的先天性疾病。根据囊肿大小(大囊型、微囊型和混合型)可分为3组。有些病例会出现自发消退;然而,此前尚未对出现消退的患者特征进行研究。此外,初始治疗的类型和时机仍存在争议。因此,我们对一家儿童中心34年来诊断为外周局限性淋巴管瘤的患者的短期自发消退情况、初次发病时的患者年龄、囊肿类型、囊肿大小和囊肿位置进行了统计分析。

方法

我们回顾性收集了153例患者的数据并查阅了病历。

结果

自发消退仅发生在大囊型或混合型;发病时年龄超过2岁的患者消退最为频繁。

结论

我们得出结论,患有大囊型或混合型淋巴管瘤的老年患者可能需要在初次发病后等待3个月以上再进行治疗。相反,微囊型预计不会在短期内消退,可能需要及时开始治疗。消退与否的差异可能取决于淋巴液流动的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/fc1d2de0e43b/gox-5-e1501-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/6cc225bf9e08/gox-5-e1501-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/c9f94881a7aa/gox-5-e1501-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/a5c7b9499a54/gox-5-e1501-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/06b2304267fb/gox-5-e1501-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/fc1d2de0e43b/gox-5-e1501-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/6cc225bf9e08/gox-5-e1501-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/c9f94881a7aa/gox-5-e1501-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/a5c7b9499a54/gox-5-e1501-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/06b2304267fb/gox-5-e1501-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bfc/5640371/fc1d2de0e43b/gox-5-e1501-g008.jpg

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